脑梗死患者颈动脉病变与眼底动脉硬化的相关性分析  

Association between carotid artery disease and fundus atherosclerosis in ischemic stroke patients

作　　者：罗晶晶[1] 衷弘熙[1] 刘冉[1] 吕志勤[1] 邢海英[1] 刘旸[1] 杨伟丽[1] 孙永安[1] 黄一宁[1] 

机构地区：[1]北京大学第一医院神经内科,100034

出　　处：《中华老年心脑血管病杂志》2015年第11期1137-1139,共3页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

摘　　要：目的探讨脑梗死患者颈动脉病变与眼底动脉硬化的相关性。方法选择脑梗死患者177例,分别进行头颅CT或MRI、颈动脉超声和眼底照相检查,评价颈动脉内膜中层厚度、颈动脉狭窄及眼底动脉硬化分级。结果177例患者中,颈动脉无病变10例(5.6%),颈总动脉内膜中层厚度增厚22例(12.4%),任意颈动脉斑块形成121例(68.4%),颈动脉狭窄24例(13.6%)。正常35例(19.8%),眼底动脉硬化改变142例(80.2%),其中Ⅰ级69例(39.0%),Ⅱ级31例(17.5%),Ⅲ级42例(23.7%)。眼底动脉硬化与颈动脉内膜中层厚度、颈动脉狭窄相关(P<0.05),但眼底动脉硬化各单项指标与颈动脉内膜中层厚度和颈动脉是否狭窄无相关性(P>0.05)。结论眼底动脉硬化与颈动脉病变存在一致性,眼底照相可作为辅助方法帮助评价全身血管情况,协助颈动脉疾病的诊断。Objective To study the association between carotid artery disease and fundus atherosclerosis in ischemic stroke patients.Methods One hundred and seventy-seven ischemic stroke patients underwent head CT/MRI,carotid artery ultrasonography,and fundoscopy to assess the severity of their carotid IMT,carotid artery stenosis and fundus atherosclerosis.Results Among the 177 patients,no carotid artery disease was detected in 10patients（5.6%）,carotid artery IMT increased in 22patients（12.4%）,carotid plaques formed in 121patients（68.4%）,carotid artery stenosis was found in 24patients（13.6%）,fundus atherosclerotic lesions were observed in 142patients（80.2%）.Fundus atherosclerosis was associated with increased carotid artery IMT and carotid stenosis（P〈0.05）.However,different single indicator of fundus atherosclerosis lesions was not associated with carotid artery IMT and carotid stenosis（P〉0.05）.Conclusion Fundus atherosclerosis is associated with carotid artery disease.Fundoscopy can thus be used as an assistant method in assessing systemic vascular condition and in diagnosing carotid artery disease.

关 键 词：脑梗死 颈动脉狭窄 眼底 动脉粥样硬化 超声检查 

分 类 号：R743.3[医药卫生—神经病学与精神病学]