老年弥漫大B细胞淋巴瘤预后影响因素  

Factors affecting the elderly diffuse large B-cell lymphoma prognosis

作　　者：陈佳[1] 刘玲玲[2] 

机构地区：[1]黄石市中心医院血液内科,湖北黄石435000 [2]黄石市中心医院肿瘤内科,湖北黄石435000

出　　处：《现代肿瘤医学》2015年第24期3645-3647,共3页Journal of Modern Oncology

基　　金：湖北省自然科学基金(编号:2010CDB07401)

摘　　要：目的:探讨老年弥漫大B细胞淋巴瘤预后影响因素。方法:回顾性分析2011年1月-2013年4月104例老年弥漫大B细胞淋巴瘤患者危险因素。结果:疗效上,总有效率为70.19%,进展为29.81%;在预后进展患者中,临床分期、IPI评分、GCB、LDH、Ki-67是老年弥漫大B细胞淋巴瘤预后进展影响因素,同时也是高危影响因素(P均<0.05),而和性别、结外侵犯、bcl-2、bcl-6、B症状、ECOG评分无关(P>0.05)。结论:影响老年弥漫大B细胞淋巴瘤预后的影响因素和患者具体疾病情况密切相关,应重视患者实际情况并选择恰当的治疗方案。Objective：To investigate elderly diffuse large B -cell lymphoma prognostic factors. Methods：A retro- spective analysis of the data of 104 elderly patients with diffuse large B - cell lymphoma was performed for the risk factors. Results：The total effective rate was 70.19% ,29.81% was progress. Clinical stage, IPI score, GCB, LDH, Ki - 67 age and lymphoma diffuse large B - cell factors were risk factors （ P 〈 0.05 ）. Gender, extranodal involvement, bcl - 2, bcl - 6, B symptoms, ECOG score were unrelated （ P 〉 0.05 ）. Conclusion： Factors influencing the elderly dif- fuse large B - cell lymphoma prognosis should be payed attention and choose suitable treatment plan.

关 键 词：老年 弥漫大B细胞淋巴瘤 预后影响因素 

分 类 号：R733[医药卫生—肿瘤]