辽宁省五市2000～2011年甲状腺癌发病、死亡现状及流行趋势分析  

Trend of Incidence and Mortality of Thyroid Cancer in Five Cities in Liaoning Province,2000～2011

作　　者：穆慧娟[1] 礼彦侠[1] 张蕊[1] 张莉梅[2] 吕艺[3] 张薇薇[4] 李海娜[5] 常征玲[6] 刘莉[1] 潘国伟[1] 

机构地区：[1]辽宁省疾病预防控制中心,辽宁沈阳110005 [2]大连市疾病预防控制中心,辽宁大连116021 [3]沈阳市疾病预防控制中心,辽宁沈阳110031 [4]鞍山市疾病预防控制中心,辽宁鞍山114002 [5]本溪市疾病预防控制中心,辽宁本溪117000 [6]丹东市疾病预防控制中心,辽宁丹东118002

出　　处：《中国肿瘤》2015年第11期889-895,共7页China Cancer

摘　　要：[目的]分析辽宁省城市2000～2011年间甲状腺癌发病率和死亡率现状及变化趋势。[方法 ]采用辽宁五市肿瘤登记处数据,计算年龄别发病率和死亡率、世界人口标化率及其年度变化百分比（annual percent change,APC）。[结果]五城市居民甲状腺癌发病世标率为4.14/10万,死亡世标率为0.33/10万。2000～2011年甲状腺癌发病世标率APC为16.55%（α=0.05,P〈0.05）,死亡世标率APC为-2.08%（α=0.05,P〉0.05）。2011年大连市男女发病世标率分别为12.94/10万和36.31/10万,为其他城市的8.78～16.18倍;男女死亡世标率分别为0.30/10万和0.46/10万。大连市发病世标率APC为22.32%（α=0.05,P〈0.05）,死亡世标率APC为0.37%（α=0.05,P〉0.05）。[结论 ]辽宁城市居民甲状腺癌发病和死亡水平及其变化趋势与国内其他地区相近。大连市甲状腺癌发病率及其增速高于辽宁省其他城市和国内其他地区,甲状腺癌筛查和影像技术普及应用可能是导致当地近些年发病率持续快速升高的主要原因,应进一步提高甲状腺癌筛查和诊疗的规范性。[Purpose] To analyze the trend of incidence and mortality of thyroid cancer in urban area of Liaoning province,2000 ～2011. [Methods] Data from 5 cancer registry sites of Liaoning province was collected,which was used to analyze the crude rate,age-specific incidence and mortality,and annual percent change（APC）. [Results] The world age-standardized incidence rate of thyroid cancer was 4.14/105,and the world age-standardized mortality rate was 0.33/105. During 2000 ～2011,APC of the incidence of thyroid cancer was 16.55%（α =0.05,P〈0.05）,and the APC of mortality of thyroid cancer was-2.08%（α=0.05,P〈0.05）. In 2011,the world age-standardized incidence rate of male and female were 12.94/105 and 36.31/105 respectively in Dalian,which was 8.78 to 16.18 times than that of other cities. Male world age-standardized mortality rate was 0.30/105 and female world age-standardized mortality rate was 0.46/105. During 2000 ～2011,the APC of incidence of thyroid cancer was 22.32%（α=0.05,P〈0.05）,and the APC of mortality of thyroid cancer was 0.37%（α=0.05,P〈0.05）. [Conclusion] In Liaoning urban areas,thyroid cancer incidence and mortality was similar to other areas in China,as well as its change trend. Thyroid cancer incidence in Dalian and its growth are significantly higher than those of other cities in Liaoning province and other regions in China. Thyroid cancer screening and imaging techniques may be the main reasons for the sustained and rapid rise of incidence in recent years,standardization of thyroid cancer screening and diagnosis and treatment should be further improved.

关 键 词：甲状腺癌 发病率 死亡率 趋势分析 辽宁 

分 类 号：R736.1[医药卫生—肿瘤]