停供碘盐对高碘地区儿童甲状腺肿大的干预效果  

Effectiveness of removing iodized salt on goiter status in children living in areas with high water iodine

作　　者：吕胜敏[1] 徐栋[1] 王玉春[2] 杜永贵[1] 贾丽辉[1] 马景[1] 

机构地区：[1]河北省疾病预防控制中心,河北石家庄050021 [2]河北省衡水市疾病预防控制中心

出　　处：《中国地方病防治》2015年第5期321-323,共3页Chinese Journal of Control of Endemic Diseases

摘　　要：目的探讨停供碘盐对高水碘地区后儿童甲状腺肿大的影响。方法在河北省衡水市随机选取3个水碘含量在150-300μg/L的高碘乡,在停供碘盐前和停供后在这3个乡分别随机选取了452和459名8-10岁儿童,用B超测量其甲状腺容积,采用我国的儿童甲状腺容积标准判定其甲状腺肿大情况。结果停供碘盐后儿童甲状腺肿大率从7.52%(34/452)下降到1.74%(8/459),P<0.01。8、9、10岁儿童的甲状腺肿大率分别从10.87%(10/92)、6.22%(12/193)、7.19%(12/167)下降到1.83%(3/164)、1.84%(3/163)、1.52%(2/132)。男孩和女孩的甲状腺肿大率分别从7.38%(18/244)、7.69%(16/208)下降到1.33%(3/226)、2.15%(5/233)。性别和年龄组甲状腺肿大率的下降均有显著统计学差异。结论河北省高碘地区停供碘盐一年半以后儿童的甲状腺肿大率显著下降。Objective To explore the impact of removing iodized salt on goiter prevalence of children living in areas with high water iodine.Methods Three towns with median water iodine（ MWI） of 150-300 μg / L were selected randomly in Hengshui City of Hebei Province of China. A total of 452 and 459 children in the 3 towns were randomly selected to measure thyroid volume by ultrasound before and after removing iodized salt respectively. Their goiter status was judged using the national criteria of child thyroid volume.Results After removing iodized salt, the overall goiter prevalence in the three towns significantly decreased from 7.52%（ 34 / 452） to 1.74%（ 8 / 459）（ P〈0.01）. The goiter prevalence in 8, 9 and 10-year-old children decreased respectively from 10.87%（ 10 / 92）, 6.22%（ 12 / 193）, 7.19%（ 12 / 167） to 1.83%（ 3 / 164）, 1.84%（ 3 / 163）, 1.52%（ 2 / 132）. The goiter prevalence in boys and girls decreased from 7.38%（ 18 / 244）, 7.69%（ 16 / 208） to 1.33%（ 3 / 226）, 2.15%（ 5 / 233） respectively. The decreases in children＇s goiter prevalence across gender and age group were all significant.Conclusion Children＇s goiter prevalence decreased significantly after removing iodized salt from their diet for about one and a half year in the high iodine areas in Hebei Province.

关 键 词：高碘 碘盐 甲状腺肿大 饮水 

分 类 号：R591.1[医药卫生—内科学]