神经内镜及显微镜下切除颅底中线区脑肿瘤的临床价值  

Curative value of resection of tumor of brain midline region of the skull base under microscope and endoscope

作　　者：宗海亮[1] 许洪升[1] 马冲[1] 尚明[1] 何晓光[1] 王椿[2] 

机构地区：[1]徐州市中心医院,江苏徐州221000 [2]上海交通大学医学院附属第一人民医院,上海200080

出　　处：《西部医学》2015年第11期1641-1643,共3页Medical Journal of West China

基　　金：国家自然科学基金(81070432)

摘　　要：目的 分析神经内镜及显微镜辅助下切除颅底中线区脑肿瘤的临床价值。方法 选取2012年11月~2014年11月间84例颅底中线区脑肿瘤患者。依据不同的实施方案分为神经内镜及显微镜辅助手术组42例（观察组）,单纯显微镜手术组42例（对照组）。对比两组脑肿瘤切除情况,两组手术时间、住院时间与出血量,以及随访两组并发症（神经功能损伤、脑脊液漏、肢体瘫痪）、复发与死亡情况。结果 观察组脑肿瘤全切率高于对照组,住院时间及出血量低于对照组。差异均有统计学意义（P〈0.05）。两组在手术时间、并发症发生率、复发率及死亡率无统计学意义（P〉0.05）。结论 神经内镜及显微镜辅助下切除颅底中线区脑肿瘤全切率高、微创安全,值得临床推荐。Objective To explore the curative value of resection of tumor of brains midline region of the skull base. Methods 84 patients with brain tumors on the center line of the skull base area were involved in the present study. De- pending on the implementation of the scheme, the patients were divided into nerve endoscope and microscope surgical group （42 cases） and simple microscope surgical group （42 cases）. The brain tumor resection, operation time, hospitali- zation time and blood loss, complications and follow-up in the two groups （neurologic injury, cerebrospinal fluid leakage, limb paralysis）, recurrence and death were observed. Results The brain tumors all cut rate of observation group was higher than that of the control group. The hospitalization time and blood loss of observation group were lower than that of the control group. The differences were statistically significant （P〈0.05）. The operation time, complications and re- currence rate and mortality of the two group had no statistical significance （P〉0.05）. Conclusion The nerve resection under endoscope and microscope assisted the center line of the skull base area is minimally invasive and safe.

关 键 词：神经内镜 显微镜 颅底脑肿瘤 疗效分析 

分 类 号：R739.91[医药卫生—肿瘤]