氟化氨银对乳牙脱矿牙本质体外再矿化的作用  

Effect of silver diamine fluoride on remineralization of demineralized dentine in primary teeth in vitro

作　　者：汤根兄[1] 李静[1] 陈银花[1] 郑红[1] 周淑[1] 刘子晗[1] 龚爱秀[1] 

机构地区：[1]南京医科大学附属南京儿童医院口腔科,江苏省210008

出　　处：《江苏医药》2015年第21期2553-2555,共3页Jiangsu Medical Journal

摘　　要：目的研究氟化氨银对乳牙脱矿牙本质体外再矿化的作用。方法 36颗离体乳牙,制备牙本质块,形成脱矿牙本质。随机均分为氟化氨银组(A组)、氟保护漆组(B组)和对照组(C组),对脱矿牙本质进行再矿化处理。采用激光扫描共聚焦显微镜对牙本质进行定量分析,扫描电镜观察牙本质表面形态。结果 A组牙本质小管完全封闭,B组部分牙本质小管封闭,C组牙本质小管完全开放。A、B组的脱矿牙本质参数值、牙本质块荧光量面积、总荧光量和病损的平均荧光量均低于C组(P<0.05),A组亦低于B组(P<0.05)。结论氟化氨银和氟保护漆均具有促进脱矿牙本质再矿化的作用,氟化氨银效果更好。Objective To investigate the effect of silver diamine fluoride on the remineralization of demineralized dentine in vitro.Methods Thirty-six primary teeth were randomly and equally divided into three groups of A（remineralized with silver diamine fluoride）,B（remineralized with flouride varnish）and C（control group）.The dentine was analyzed quantificationally by confocal laser scanning microscope.The surface morphology was observed by scanning electron microscope.Results The dentin tubules in group A were completely closed,which were partly closed in group B and open in group C.The fluorescence area,total fluorescence intensity and mean fluorescence intensity were lower in groups of A and B than those in group C（P〈0.05）,which were lower in group A than those in group B（P〈0.05）.Conclusion Silver diamine fluoride and flouride varnish can promote the remineralization of demineralized dentine while the effect of the former was stronger.

关 键 词：氟化氨银 氟保护漆 乳牙 脱矿牙本质 

分 类 号：R778[医药卫生—眼科]