Cirrus HD-OCT测量近视患者角膜厚度的应用研究  

Corneal thickness measured by Cirrus HD-OCT in myopic eyes

作　　者：马晶[1] 刘鹤南[1] 杨飏[1] 杜长虹[1] 张桂新[1] 曹楠珏 夏丽坤[1] 

机构地区：[1]中国医科大学附属盛京医院眼科激光手术中心,辽宁省沈阳市110004

出　　处：《眼科新进展》2015年第11期1077-1080,共4页Recent Advances in Ophthalmology

摘　　要：目的对比分析Cirrus HD-OCT和A超测量中央角膜厚度的差异性及相关性,并探索Cirrus HD-OCT角膜测厚与眼轴长度的关系。方法回顾性研究2015年1月至4月拟在我院行角膜激光矫正近视手术的患者42例（84眼）,按眼轴长度分为三组,A组（32眼）：眼轴长度24~26 mm组;B组（31眼）：眼轴长度〉26~28 mm组;C组（21眼）：眼轴长度〉28 mm组。利用Cirrus HD-OCT和A超分别测量患者的中央角膜厚度,用配对t检验来比较两种方法测厚的差异性,用Pearson分析两种方法测厚的相关性,用两独立样本t检验比较不同眼轴组角膜厚度的差异性。结果 A组Cirrus HD-OCT和A超测量患者的中央角膜厚度分别为（539.91±30.74）μm和（540.22±30.79）μm,测量结果差异无统计学意义（t=0.230,P〉0.05）。B组Cirrus HDOCT和A超测量患者的中央角膜厚度分别为（543.94±31.75）μm和（544.36±33.58）μm,测量结果差异无统计学意义（t=0.304,P〉0.05）。C组Cirrus HD-OCT和A超测量患者的中央角膜厚度分别为（548.19±25.81）μm和（545.43±26.70）μm,测量结果差异也无统计学意义（t=1.766,P〉0.05）。Cirrus HD-OCT和A超测量结果具有显著正相关性（r=0.97,P〈0.05）。三组间Cirrus HD-OCT角膜测厚的差异性比较,A组与B组测量值差异无统计学意义（t=0.504,P〉0.05）、A组与C组测量值差异无统计学意义（t=0.999,P〉0.05）、B组与C组测量值差异无统计学意义（t=0.499,P〉0.05）。Cirrus HD-OCT测量角膜厚度与眼轴长度无相关性。结论 Cirrus HD-OCT测量中央角膜厚度结果可靠,且Cirrus HD-OCT和A超的测量结果显著的正相关。Cirrus HD-OCT角膜测厚与眼轴长度无关。Objective To investigate and analyze the differences and correlations between central corneal thickness （CCT） measured by Cirrus HD-OCT and ultrasonic pachymetry, and find out the correlations between corneal thickness by Cirrus HD-OCT and ocular axial length. Metl=ods The retrospective study measured CCT of 42 pa- tients（84 eyes） who prefer to perform corneal refractive surgery correcting myopia by Cirrus HD-OCT and ultrasonic pachymetry. The patients were divided into three groups by ocular axial length： group A： 24 - 26 mm （ 32 eyes） ; B ： 25 - 28 mm （ 31 eyes） ; C ： 〉 28 mm（21 eyes）. CCT was measured by Cirrus HD-OCT and ultrasonic pachymetry, the difference of two measurements was compared by paired t-test, and the Pearson analy- sis was applied to analyze their correlation. Results In group A, CCT measured by Cirrus HD-OCT was（539.91 ±30.74） μm, and by ultrasonic pachymetry was（540.22 ± 30.79） μm,there was no statistical difference between the two methods（ t = 0. 230,P 〉 0.05 ）. In group B, CCT measured by Cirrus HD-OCT was （543.94 ± 31.75 ） μm, and by ultrasonic pachymetry was（544.36 ±33.58）μm,there was no statistical difference be- tween the two methods（ t = 0. 304 ,P 〉 0.05 ）. In group C, CCT measured by Cirrus HD- OCT was（548.19 ±25.81 ） μm,and by ultrasonic pachymetry was （545.43 ±26.70） μm, there was no statistical difference between the two methods（ t = 1. 766 ,P 〉 0.05 ）. Signif- icant correlations were found between the two methods（ r = 0.97 ,P 〈 0.05 ）. No correla-tion was found between ocular axial length and central corneal thickness measured by Cirrus HD-OCT. The results between group A and B was not statistically different using two samples of the t-test comparison（ t = 0.504 ,P 〉 0.05 ） ; The results be- tween group A and C was not statistically different using two samples of the t-test comparison（ t = 0.999 ,P 〉 0.05 ） ;the re- sults between B and C was not statistically different using two

关 键 词：CIRRUS HD-OCT 超声测厚仪 角膜厚度 眼轴长度 

分 类 号：R778.11[医药卫生—眼科]