双源CT全脑灌注对短暂性脑缺血发作脑血流动力学变化的评价  

The evaluation of cerebral hemodynamic changes of transient ischemic attack in dual source CT perfusion

作　　者：卞力勇[1] 

机构地区：[1]福建省立医院放射科,福州350001

出　　处：《创伤与急诊电子杂志》2015年第4期43-44,42,共3页Journal of Trauma and Emergency(Electronic Version)

摘　　要：目的探讨双源CT全脑灌注对短暂性脑缺血发作(transient ischemic attack,TIA)血流动力学改变的临床价值。方法临床拟诊TIA患者20例,均在症状出现24小时内行头颅CT平扫及CT Perfusion检查,将脑血流异常区与健侧对应区的情况做对比分析。结果 20例患者中,15例患者出现腔梗改变。20例患者均出现灌注异常区,患侧达峰时间(time to peak,TTP)时间较健侧明显延长(P<0.05),同时15例患者平均通过时间(mean transit time,MTT)延长(P<0.05)。15例患者脑血容量(cerebral blood volum,CBV)较健侧略有增加(P>0.05),所有患者脑血流量(cerebral blood flow,CBF)无明显改变。结论双源CT全脑灌注能较好地反映TIA脑血流动力学变化,为早期诊断、治疗提供客观依据。Objective To explore cerebral hemodynamic changes of transient ischemic attack（TIA）in dual source CT perfusion（CTP）. Method Twenty patients with suspected TIA underwent plain CT and CTP within 24h of the onset of symptoms. The results of the abnormal regions of the cerebral blood flow and the contralatcral normal region were comparatively analyzed. Result Lacunar infarction were found in 15 out of 20 patients who were all with abnormal perfusion area. The imaging results demonstrated that significantly larger time to peak（TTP） delay in 20 patients with abnormal perfusion area was found compared with that in contralateral normal region（P 〈 0.05）,and mean transit time（MTT） delay was longer in 15 patients with abnormal perfusion area than that in contralateral normal region（P 〈 0.05）. There is a slight increase of cerebral blood volum（CBV） in 15 patients（P〈0.05）,and no significant change of cerebral blood flow（CBF） was found.Conclusion CTP with dual source CT can accurately display cerebral hemodynamic changes of transient ischemic attack（TIA） and provides objective evidence for early diagnosis and treatment.

关 键 词：短暂性脑缺血发 体层摄影术 X线计算机 灌注成像 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R816.1[医药卫生—临床医学]