抗血管生成治疗机制及其在转移性乳腺癌中的应用研究进展  

Research Progress of Anti-angiogenesis Therapy Mechanism and which Applied in Metastatic Breast Cancer

作　　者：张连伟[1] 刘健[1] 宋云飞[1] 

机构地区：[1]福建中医药大学

出　　处：《按摩与康复医学》2015年第21期6-9,共4页Chinese Manipulation and Rehabilitation Medicine

基　　金：国家临床重点建设专科项目:乳腺癌循环肿瘤细胞及其单细胞多基因检测的临床意义(No.2011-cx-16);乳腺癌紫杉醇及曲妥珠单抗耐药分子机制的比较及mTor抑制剂对耐药逆转的研究(No.2015J01381)

摘　　要：乳腺癌是我国女性发病率最高的恶性肿瘤之一，传统疗法如化疗、放疗、内分泌疗法等虽延长转移性乳腺癌患者的生存时间，但患者整体预后较差。血管调控学说认为肿瘤远处转移依赖血管调控的失衡，联合或单独应用抗血管生成治疗转移性乳腺癌解一种新思路。本文综述抗血管生成治疗转移性乳腺癌的进展。Breast cancer is one of the malignant tumors with highest incidence in China, traditional therapies such as chemotherapy, radiotherapy and endocrinotherapy can lengthen survival time of patients with metastatic breast cancer, but the overall prognosis is poor. Vascular control theory re-gards that distant metastasis tumor is due to vascular regulation imbalance, the combined or separate application of anti-angiogenic therapy on meta-static breast cancer is a new method. This paper summarizes the progress of anti-angiogenesis therapy for metastatic breast.

关 键 词：转移性乳腺癌 抗血管生成 机制 治疗药物 综述 

分 类 号：R737.9[医药卫生—肿瘤]