神经内科记忆门诊认知障碍患者分布情况及治疗依从性随访观察  

Investigation for distribution of the patient suffered with cognitive disorder and the compliance of those patients at memory clinic of neurology

作　　者：冯靓[1] 吴文秀[2] 谢莹[3] 王贞[1] 肖美娟[1] 何金彩[1] 

机构地区：[1]温州医科大学附属第一医院神经内一科,浙江温州325015 [2]温州医科大学附属第一医院康复科,浙江温州325015 [3]荆州市长江大学附属第一医院精神科,湖北荆州434000

出　　处：《温州医科大学学报》2015年第11期827-830,共4页Journal of Wenzhou Medical University

基　　金：温州市科技局科研基金资助项目(Y20120152)

摘　　要：目的：观察温州医科大学附属第一医院神经内科记忆门诊认知障碍患者的分布情况,了解影响患者治疗依从性的因素。方法：连续登记2012年11月-2013年1月间在温州医科大学附属第一医院神经内科记忆门诊就诊的认知障碍患者,确定病因分型和疾病严重程度分布。随访（56±7）d,统计随访者及失访者例数及影响因素,采用logistic回归分析影响治疗依从性的因素。结果：共筛查了93例记忆障碍患者,入组60例,其中阿尔茨海默病（AD）源性认知障碍40例,占66.67%;血管性认知障碍7例,额颞叶痴呆（FTD）2例,其他原因导致认知障碍11例。不同病情严重程度均占一定比率,其中轻度认知功能障碍11例,占18.33%;中重度痴呆患者合计34例,占56.67%。对8个可能影响依从性的因素进行分析发现,文化程度为独立相关因素（P=0.01,OR=2.3,95%CI：1.19~4.45）。结论：温州医科大学附属第一医院神经内科记忆门诊认知障碍患者的首位病因为AD源性认知障碍,中重度认知障碍患者所占比率高,患者的文化程度与治疗依从性独立相关。Objective： To observe the distribution of the outpatients suffered with cognitive disorder at memory clinic of neurology in our hospital. To find the factors which effected on the compliance of those pa- tients. Methods： Consecutive cases of outpatients complaining with cognitive disorder at neurology clinic were collected from Nov. 2012 to Jan. 2013, the different causes for cognitive disorder of patients were definited and the degree of severity was described.2. Prospective following-up： all the cases were followed up to 56：t：7 days after registration, the factors with effected on the compliance of the patients were collected, non-conditional lo- gistic regressions analysis was adopted as statistical method. Results： Total 93 cases complaining with memory disorder were screened, 60 patients with cognitive disorder were chosen, among them there were 40 cases of A1- zheimer＇s disease （AD） type, with the percent of 66.67%, 7 cases with cognitive impairment of vascular type, 2 cases of frontotemporal dementia （FTD）, and 11 cases of other causes. Account to the degree of the severity, there were 11 cases with mild cognitive impairment （MCI）, the percent was 18.33% and the cases of middle-severe pa- tient were 34, the percent was 57%. By the study of the 8 possible factors, it showed that the degree of education was the independent factor （P=-0.01, OR=2.3, 95%CI： 1.19 - 4.45） for the compliance of those patients. Conclu- sion： Cognitive impairment of AD type is the first cause of the patients with cognitive disorder at our memory clinic, middle-severe cognitive disorder patients take a high percent, the degree of education is the independent factor for compliance of the patients.

关 键 词：认知障碍 记忆门诊 阿尔茨海默病 血管性痴呆 依从性 

分 类 号：R74[医药卫生—神经病学与精神病学]