急性白血病患者伴发肛瘘的治疗  

Surgical treatment of anorectal fistula in patients of acute leukemia

作　　者：胡云龙[1] 马木提江·阿巴拜克热[1] 艾尔哈提·胡赛音[1] 赵亮[1] 杨鹏[1] 刘学[1] 张管平[1] 

机构地区：[1]新疆医科大学第一附属医院肛肠科,乌鲁木齐830011

出　　处：《中华普通外科杂志》2015年第11期897-899,共3页Chinese Journal of General Surgery

基　　金：新疆维吾尔自治区自然科学基金资助项目（2013211A077）

摘　　要：目的分析急性白血病患者伴发肛瘘的临床诊治特点及手术时机选择。方法回顾性分析2010—2015年新疆医科大学第一附属医院急性白血病伴发肛瘘患者42例的临床资料，根据化疗前后手术时机的选择分为先手术后化疗组（A组）与先化疗后手术组（B组），采用χ2、t检验行临床相关指标的对比。结果A组术后1d中性粒细胞计数较B组减少明显，差异有统计学意义（χ2=8．077，P=0．004），其余各项指标差异无统计学意义（P〉0．05），B组患者术后再次发生感染的可能较小。结论急性白血病患者伴发肛瘘时，化疗前后的手术时机选择与患者预后有一定的关系，先化疗后手术可能对改善患者的预后有帮助。Objective To evaluate treatment and operation timing of anal fistula in acute leukemia patients. Methods Clinical data of 42 acute leukemia patients with anal fistula from 2010 to 2015 in First Hospital of Xinjiang Medical University were evaluated according to the choice of operation time. Patients were divided into two groups undergoing surgery before chemotherapy, （group A ） and surgery after chemotherapy （group B）. Clinical analysis was performed using χ2 or t test and correlation index. Results Neutrophil count in group B was lower than that in group A （χ 2 = 8. 077 ,P = 0. 004）. Chemotherapy before surgery regime reduces the incidence of infection. Conclusions Chemotherapy before surgery may improve the prognosis of anorectal fistula patients of acut leukemia.

关 键 词：直肠瘘 白血病 脓肿 结直肠外科手术 

分 类 号：R733.71[医药卫生—肿瘤]