增强型体外反搏治疗进展性缺血性卒中的临床疗效及其对神经功能的影响  

Clinical Effect of Enhanced External Counterpulsation on Progressive Ischemic Stroke and Its Impact on Neurological Function

作　　者：肖剑伟 蔡旭[2] 黄宗青[1] 张志[1] 周国强 

机构地区：[1]广东省深圳市第四人民医院神经内科,广东省深圳市518000 [2]广东医学院附属福田医院香蜜湖风湿病分院

出　　处：《实用心脑肺血管病杂志》2015年第9期102-104,共3页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：2014年深圳市福田区卫生公益性科研项目(FTWS2014073)

摘　　要：目的探讨增强型体外反搏治疗进展性缺血性卒中的临床疗效及其对神经功能的影响。方法选取2013年11月—2015年5月广东省深圳市第四人民医院神经内科诊治的进展性缺血性卒中患者80例,根据随机数字表法分为治疗组和对照组,各40例。对照组患者给予常规治疗,治疗组患者在对照组基础上给予增强型体外反搏治疗,两组患者治疗疗程均为1个月。比较两组患者临床疗效,治疗前后美国国立卫生研究院卒中量表(NIHSS)评分、Rankin评分及肱动脉超声检查指标〔肱动脉血流介导的内皮依赖性舒张功能(FMD)及非内皮依赖性舒张功能(NMD)〕。结果治疗组患者临床疗效优于对照组(P<0.05)。治疗前两组患者NIHSS评分和Rankin评分比较,差异无统计学意义(P>0.05);治疗后治疗组患者NIHSS评分和Rankin评分低于对照组(P<0.05)。治疗前两组患者FMD和NMD比较,差异无统计学意义(P>0.05);治疗后治疗组患者FMD和NMD高于对照组(P<0.05)。结论增强型体外反搏治疗进展性缺血性卒中的临床疗效确切,能有效改善患者神经功能。Objective To investigate the clinical effect of enhanced external counterpulsation on progressive ischemic stroke and its impact on neurological function. Methods From November 2013 to May 2015, a total of 80 patients with progressive ischemic stroke were selected in the Department of Neurology,the Fourth People＇ s Hospital of Shenzhen,and they were divided into control group and treatment group according to random number table. Patients of control group received conventional treatment,while patients of treatment group received extra enhanced external counterpulsation; both groups treated for one month. Clinical effect,NIHSS score,Rankin score,flow- mediated vasodilation（ FMD） and nitroglycerin- mediated dilation（ NMD） before and after treatment were compared between the two groups. Results The clinical effect of treatment group was statistically significantly better than that of control group（ P〈0. 05）. No statistically significant differences of NIHSS score or Rankin score was found between the two groups before treatment（ P〉0. 05）,while NIHSS score and Rankin score of treatment group were statistically significantly lower than those of control group after treatment（ P〈0. 05）. No statistically significant differences of FMD or NMD was found between the two groups before treatment（ P〉0. 05）,while FMD and NMD of treatment group were statistically significantly higher than those of control group after treatment（ P〈0. 05）. Conclusion Enhanced external counterpulsation has certain clinical effect in treating progressive ischemic stroke,can effectively improve the neurological function.

关 键 词：卒中 增强型体外反搏 治疗结果 神经功能 

分 类 号：R743[医药卫生—神经病学与精神病学]