脑膜瘤瘤周水肿相关因素分析  

Analysis the related factors associated with meningioma peritumoral edema

作　　者：杨磊[1] 赵海康[1] 李瑞春[1] 王军红[1] 

机构地区：[1]西安医学院第二附属医院神经外科,陕西西安710038

出　　处：《中华肿瘤防治杂志》2015年第B11期29-30,共2页Chinese Journal of Cancer Prevention and Treatment

摘　　要：目的探讨脑膜瘤瘤周水肿的相关因素。方法将西安医学院第二附属医院2014—05—2015—05接收的18例脑膜瘤患者作为研究对象，对其影像学资料进行回顾性分析，并采用Logistic回归分析法对相关因素进行分析。结果脑膜瘤瘤周水肿与肿瘤包膜是否完整、肿瘤组织中血管内皮生长因子（vascularendothelialgrowthfactor，VEGF）的表达水平呈高度相关，P〈0．05。结论正常脑屏障受到脑膜瘤的破坏为瘤周水肿的解剖基础，肿瘤细胞所分泌的VEGF为脑水肿最为直接的原因。OBJECTIVE To explore the relevant factors meningioma peritumoral edema. METHODS 18 cases of meningioma patients in our hospltal received the study, were retrospectively analyzed imaging data, and the use of Logis- tic regression analysis of the relevant factors were analyzed. RESULTS Meningioma peritumoral edema and tumor capsule is complete, the expression levels of VEGF in tumor tissue was highly correlated （P〈0. 05）. CONCLUSION Normal brain harrier disruption by the anatomy of meningioma peritumoral edema, tumor cells secrete VEGF is the most direct cause cerebral edema.

关 键 词：脑膜瘤 瘤周水肿 相关因素 

分 类 号：R739.41[医药卫生—肿瘤]