不同强度低频重复经颅磁刺激对脑卒中后非流畅性失语的疗效  

Effect of Intensity of Repetitive Transcranial Magnetic Stimulation on Nonfluent Aphasia after Stroke

作　　者：胡雪艳[1,2] 张通[1,2] 刘丽旭[1,2] 何静杰[1,2] 刘平[1,2] 杨宇琦[1,2] 毕晓辉[1,2] 

机构地区：[1]中国康复研究中心北京博爱医院神经康复科,北京市100068 [2]首都医科大学康复医学院,北京市100068

出　　处：《中国康复理论与实践》2015年第11期1294-1297,共4页Chinese Journal of Rehabilitation Theory and Practice

基　　金：国家自然科学基金项目(No.81171243)

摘　　要：目的探讨不同强度低频(1 Hz)重复经颅磁刺激(r TMS)刺激右侧大脑半球Broca区镜像区对脑卒中后非流畅性失语患者语言功能恢复的影响。方法 40例脑卒中后非流畅性失语患者等分为低强度组和高强度组,低强度组r TMS治疗每天1次,高强度组每天2次,均每次10 min,共10 d。治疗前后及治疗结束2个月后应用西方失语症成套测验(WAB)进行评估。结果治疗后,高强度组自发言语、听理解、复述、命名、失语商(AQ)明显优于低强度组(P<0.01);治疗结束2个月后,高强度组自发言语、复述、AQ优于低强度组(P<0.05)。结论高强度低频r TMS刺激右侧大脑半球促进脑卒中后非流畅性失语患者语言功能恢复效果更明显,治疗效果可长期维持。Objective To explore the effect of intensity of 1 Hz repetitive transcranial magnetic stimulation （rTMS） to right Broca＆#39;s ho-mologue on nonfluent aphasia after stroke. Methods 40 inpatients were equally divided into low-intensity group and high-intensity group, who received rTMS （1 Hz for 10 minutes） once a day and twice a day respectively for 10 days. They were assessed with Western Aphasia Battery （WAB） before and after intervention, and 2 months after intervention. Results The scores of content and fluency, auditory compre-hension, naming, repetition and AQ improved more in the high-intensity group than in the low-intensity group （P〈0.01）. It maintained more for 2 months in the scores of content and fluency, repetition and AQ （P〈0.05）. Conclusion High-intensity rTMS can promote the improve-ment of speech in patients with nonfluent aphasia after stroke that remains for a long term.

关 键 词：脑卒中 非流畅性失语 重复经颅磁刺激 康复 

分 类 号：R743.3[医药卫生—神经病学与精神病学]