不同放疗分割方式治疗上腔静脉综合症疗效观察  

Clinical observation of Segmentation way different radiotherapy in the treatment of superior vena cava syndrome

作　　者：李小明[1] 牛德森[1] 

机构地区：[1]内蒙古包钢医院肿瘤放疗科,内蒙古包头014010

出　　处：《疾病监测与控制》2015年第11期779-780,共2页Journal of Diseases Monitor and Control

摘　　要：目的探讨不同放疗分割方式治疗上腔静脉综合症疗效。方法对60例患者回顾性分析其中30例采用大分割结合常规分割放疗,颈胸联合野(即大T野):纵隔和锁骨上下野,DT350 c GY/d,6次后改为常规分割三位适形治疗200c GY/d,10到12次;15例采用大分割放疗;15例采用常规分割放疗。结果大分割结合常规分割放疗1周内上腔静脉综合症迅速缓解率为(96.6%)明显高于常规分割组缓解率(53.3%),差异有统计学意义(P﹤0.05)止痛效果明显;3月后的复发率(6.6%)低于大分割组的(60.0%)及常规分割组(46.7%)差异有统计学意义(P﹤0.05)结论大分割结合常规分割三位适形放射治疗,症状缓解优于常规分割放疗,复发率低于大分割治疗。Objective To investigate the effects of different radiotherapy segmentation methods in the treatment of superior vena cava syndrome curative effect. Methods 60 cases of patients including 30 cases were retrospectively analyzed by splitting combined with conventional radiotherapy, big chest neck joint field（that is, the bigger T wild） mediastinal and supraclavicular, DT350 c GY per day, 6 times instead of the conventional segmentation three conformal therapy after 200 c GY/day to 12 times.15 cases with large divided radiotherapy; 15 cases with conventional radiotherapy. Results Large segmentation combined with conventional radiotherapy segmentation within 1 week rapid response rate for superior vena cava syndrome（96.6%） group is significantly higher than the conventional segmentation remission rate（53.3%）, difference was statistically significant（P﹤0.05） analgesic effect is obvious; Recurrence rate after march（6.6%） below the divided group（60.0%） and conventional segmentation group（46.7%） difference was statistically significant（P﹤0.05）. Conclusion The split three conformal radiotherapy combined with conventional segmentation, symptoms is、uperior to the conventional radiotherapy, recurrence rate is lower than the big split treatment.

关 键 词：上腔静脉综合症 放疗 大分割治疗 

分 类 号：R730.55[医药卫生—肿瘤]