肝癌局部消融治疗后的疗效及影像学评价  

Local Ablation Treatment Effects and Imaging Evaluation for Primary Liver Cancer

作　　者：赵鹏[1] 郑加生[1] 

机构地区：[1]首都医科大学附属北京佑安医院肿瘤微创介入治疗中心,北京100069

出　　处：《医学综述》2015年第22期4088-4090,共3页Medical Recapitulate

基　　金："十二五"国家科技支撑计划(2012BAI15B08);国家自然科学基金(81472328)

摘　　要：局部消融治疗具备快速、安全、有效的特点,已普遍运用于原发性肝癌的治疗。肝脏供血70%来自门静脉系统,肝癌肝内转移几乎均通过门静脉系统,因此局部消融是否精准,需要进行术后的疗效评价及局部肿瘤复发监测。消融病灶的同时,对其周围正常肝组织进行适当消融,形成安全消融边缘,从而可以最大程度地降低肝内转移和(或)微血管侵犯的风险。但是,消融区域周围非肿瘤组织充血引起的炎症反应会掩盖局部肿瘤复发的证据,因此须严格对比影像结果明确有无复发依据。该文就目前影像学检查对肝癌消融治疗后的疗效评价进行综述,并探讨安全消融边缘对于降低局部肿瘤复发率的重要意义。Local ablation therapy has been widely used in the treatment of primary liver cancer because of its fast,safe and effective features. It is well known that 70% of liver blood supply is from the portal system, so intrahepatic metastasis of liver cancer almost all happens through this way. The evaluation and monitoring of local tumor recurrence after ablation is needed to know whether local ablation is accurate. The complete ablation of the tumor must include appropriate formation of the safety edge after ablation therapy, in order to completely cover the tumor area and minimize the risk of intrahepatic metastasis and/or microvaseu- lar invasion. However, the hyperemia-induced inflammatory response in the non-tumor tissue region after abla- tion would hide the evidence of local tumor recurrence, so it is most necessary to contrast imaging results in order to find the recurrence evidence. Here reviews the current imaging studies to evaluate the efficacy of ablation for liver cancer after treatment, and discuss the the significance of ablation safety edges for reducing the local recurrence rate.

关 键 词：原发性肝癌 消融 安全消融边缘 影像学监测 

分 类 号：R735.7[医药卫生—肿瘤]