角巩膜生物力学性能测量技术的研究进展  

The research advance of measuring techniques on corneoscleral constitutive parameters

作　　者：包芳军[1] 邓曼丽[1] 王勤美[1] 

机构地区：[1]温州医科大学附属眼视光医院,325027

出　　处：《中华眼科杂志》2015年第11期875-880,共6页Chinese Journal of Ophthalmology

基　　金：温州市重点科技创新团队项目（C20120009-04）;国家自然科学基金青年科学基金项目（81300807）

摘　　要：近视眼及圆锥角膜的发生、发展与巩膜及角膜的生物力学性能改变密切相关.准确测量角巩膜生物力学性能在眼部疾病的诊断、眼科手术技术的改进、眼部生物参数的测量和眼科医疗器械的研发等方面具有非常重要的意义.角巩膜组织构成眼球外壁,主要由致密交错的胶原纤维束和细胞外基质组成.角巩膜内部各层及各区域间胶原纤维的直径、间隙和数量分布的差异,使其生物力学特征颇为复杂,表现为非线弹性、黏弹性、各向异性、区域差异性和年龄相关性等.随着医疗检查诊断技术的发展,临床逐渐认识到眼部生物力学性能的重要性,但由于多数眼科医师对眼部生物力学性能的测量技术仍不甚了解,故笔者就国际上角巩膜生物力学性能测量技术的发展进行综述,为临床选取合适的测量平台与方法测量和研究角巩膜生物力学性能提供帮助.The occurrence and development of myopia and keratoconus is closely related to the changes of scleral and corneal biomechanical properties.The accurate measurement of biomechanical properties for corneoscleral fissure is very important on diagnosis of eye diseases, improvement of ocular operation, ocular biological parameter measurement and invention of ophthahnic instrument.Corneoscleral tissue, composed of bundles of compact and staggered collagen fiber and extracellular matrix, constitute the outer surface of the eyeball.The inhomogeneous distribution of the diameter, gap and amount of collagen fiber, makes its biomechanical characteristics really complex, characterized by nonlinear, viscoelastic, anisotropic, regional variation and age-related variation and etc.With the development of medical diagnostic technology, the importance of the ocular biomechanical property measurement is increasingly recognized.Nevertheless, measuring technology on ocular biomechanics properties are still not well understood by the majority of ophthalmologists.In order to facilitate the researchers to select a suitable measuring platform and method, the development of international corneoscleral biomechanical propertiy measuring technology was reviewed in this article.

关 键 词：巩膜 角膜 生物力学 诊断技术 眼科 

分 类 号：R772[医药卫生—眼科]