血栓痔患者痔组织中一氧化氮及氧自由基水平变化的临床研究  

Levels Change of NO and Oxygen Free Radicals in Hemorrhoids Tissue of the Thrombosed Hemorrhoids Patients.. Clinical Research

作　　者：杨峰[1] 易静[1] 陈小岚[1] 田萍[1] 刘民生[1] 马翔[1] 盛光[1] 徐敏[1] 庄树彤[1] 

机构地区：[1]广东省深圳市第二人民医院肛肠外科,广东深圳518035

出　　处：《中国肛肠病杂志》2015年第10期15-16,共2页Chinese Journal of Coloproctology

基　　金：深圳市科创委项目（JCYJ20130401113946478）

摘　　要：为探讨一氧化氮和氧自由基在血栓痔形成过程中的作用，选取我科住院的15例血栓痔患者作为试验组，15例非血栓痔患者作为对照组，对两组切除的痔组织进行匀浆提取组织液，并检测组织液中的一氧化氮及抗活性氧能力。结果显示，试验组痔组织中一氧化氮水平、抗活性氧能力均明显低于对照组，P〈0．05。结果表明，血栓痔组织中，一氧化氮水平降低，氧自由基水平升高。痔血栓形成可能与一氧化氮、氧自由基水平失衡有关。Abstract In order to explore the role of NO and oxygen free radicals in the formation of thrombosed hem- orrhoids,authors selected 15 cases of thrombosed hemorrhoids as trial group,and 15 cases of non-thromo- hosed hemorrhoids as control group;then extracted tissue fluid homogenate from removed hemorrhoids tis- sue and detected the NO contents and their ability to anti-active oxygen.As results,in trial group NO level and its anti-active oxygen ability were significantly lower than that in control group（ P〈0.05）.Results show that in thromobosed hemorrhoid tissue lowed level of NO and increased level of oxygen free radicals leading the imbalance of both could be a cause of the formation of hemorrhoid＇s thrombus.

关 键 词：痔 血栓 一氧化氮 氧自由基 

分 类 号：R743.33[医药卫生—神经病学与精神病学]