调强放射治疗与快速拉弧照射技术在鼻咽癌放射治疗中的剂量学研究  

Radiation dosimetric study of IMRT and RapidArc technology in radiotherapy of nasopharyngeal carcinoma

作　　者：杨静[1] 白雪[1] 苏锋[1] 赵凯[1] 

机构地区：[1]浙江省肿瘤医院物理室,杭州310022

出　　处：《浙江医学》2015年第20期1674-1676,共3页Zhejiang Medical Journal

摘　　要：目的比较鼻咽癌患者在接受放射治疗时,调强放射治疗(IMRT)与快速拉弧照射(RapidArc)技术之间的剂量学差异,为临床放射治疗技术选择提供参考。方法选取8例鼻咽癌患者,对每例患者均采取IMRT与RapidArc技术设计放射治疗计划,采取统—剂量归—方法(PTVV=95%)比较靶区及危及器官的受量。结果 RapidArc技术相比IMRT技术有部分更高的靶区照射剂量(均P<0.05)。对于危及器官,RapidArc技术将会使脑干和脊髓受到更高剂量的照射(均P<0.05),其它正常组织照射剂量均无统计学差异。结论RapidArc技术在剂量学上相比IMRT技术没有明显优势。Objective To compare the dosimetric difference of intensity modulation radiated therapy（IMRT） with RapidArc technique in treatment of early nasopharyngeal carcinoma （NPC）. Methods Eight early NPC patients were planned in both IMRT and RapidArc technique with the unified dose and normalization method （PTVV=95%）. The received dose of radiation in both tar- gets and organs were compared between two techniques. Results The high dose region for targets in RapidArc was much more than that in IMRT（P〈0.05）. For endanger organs, as brain stem and spinal cord received higher radition by RapidArc（P〈 0.05）. There was no statistical difference in other normal tissues between two techniques. Conclusion Compared with IMRT plan RapidArc does not posse any significant advantage.

关 键 词：鼻咽癌 放射治疗 剂量学 

分 类 号：R739.63[医药卫生—肿瘤] R730.55[医药卫生—临床医学]