结直肠癌患者外周血循环肿瘤细胞的检测及临床研究进展  

Research progress on circulating tumor cells and their detection in colorectal cancer

作　　者：孙文洁[1] 章真[1] 

机构地区：[1]复旦大学附属肿瘤医院放疗科,复旦大学上海医学院肿瘤学系,上海200032

出　　处：《中国癌症杂志》2015年第11期854-860,共7页China Oncology

摘　　要：结直肠癌是最常见的恶性肿瘤之一,虽然综合治疗的开展使其疗效有较大改善,但仍有较多患者死于术后的复发和转移。循环肿瘤细胞(circulating tumor cell,CTC)来源于肿瘤组织,与肿瘤转移及预后密切相关。对CTC检测方法及其在结直肠癌中的临床研究进行综述。Colorectal cancer is one of the most common malignant tumors. Though the development of multidisciplinary therapy has largely improved the therapy effects, many patients still died of local recurrence and metastases after surgery. Circulating tumor cell （CTC） originates from primary tumor tissues and has a close relationship with cancer metastases and prognosis. This review summarizes the CTC detection methods and relevant clinical research on CTC in recent years.

关 键 词：结直肠癌 循环肿瘤细胞 检测 治疗 

分 类 号：R735.3[医药卫生—肿瘤]