检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
作 者:李金虎[1] 李纲[1] 陈卫国[1] 严春寅[1]
机构地区:[1]苏州大学附属第一医院泌尿外科,江苏215006
出 处:《国际泌尿系统杂志》2015年第6期818-820,共3页International Journal of Urology and Nephrology
摘 要:目的 探讨年龄对前列腺特异抗原4 ~ 10μg/L患者癌变检出及病情影响的研究.方法 回顾性分析2003年2月至2014年6月收治的368例不同年龄段前列腺特异抗原(PSA)4~10μg/L患者的临床资料,根据年龄段分为4组:<60岁组(Ⅰ组,43例)、60~69岁组(Ⅱ组,157例)、70~79岁组(Ⅲ组,142例)、>80岁组(Ⅳ组,26例),368例患者均行前列腺穿刺活检术,临床病理资料完整;比较各组患者年龄与前列腺癌检出率的关系,并对各组患者年龄与Gleason评分及临床分期进行相关性分析.结果 Ⅰ、Ⅱ、Ⅲ、Ⅳ组肿瘤穿刺阳性率分别为11.63%(5/43) 、29.30% (46/157)、30.28%(43/142)、38.46% (10/26).穿刺阳性率与年龄成正相关,各组前列腺癌检出率比较有统计学意义(Z =4.078,P<0.01).Ⅰ、Ⅱ、Ⅲ、Ⅳ组的Gleason评分≥7患者分别为1例(20%)、11例(23.91%)、30例(69.77%)、7例(70%),与年龄无显著相关性(P=0.23).Ⅰ、Ⅱ、Ⅲ、Ⅳ组中局限性前列腺癌患者分别为3例(60%)、32例(69.57%)、33例(76.74%)、4例(40%);局部进展性前列腺癌分别为1例(20%)、12例(26.09%)、8例(18.60%)、4例(40%);进展性前列腺癌分别为1例(20%)、2例(4.35%)、2例(4.65%)、2例(20%);各分期与年龄均无显著相关性(P =0.101 6、P=0.2852、P=0.349 1).结论 PSA4~ 10μg/L患者前列腺癌的检出率随着年龄增加而增高,肿瘤恶性程度和转移风险与年龄无明显相关性。Objectives To investigate the correlation between the age and cancer detection of patients whose prostate specific antigen is in the range of 4 ~ 10μg/L and research on the effects of illness.Methods A retrospective analysis in February 2003 to June 2014 treated 368 cases of different age paragraph the prostate specific antigen(PSA) 4~10 μg/L in patients with clinical data,according to the age group is divided into four groups:〈60 years old group(Igroup,43 cases),and 60~69 years group(Ⅱ group,157 cases),70~ 79 age group(Ⅲ group,142 cases),〉 80-year-old group (Ⅳ group,26 cases),prostate biopsy in 368 patients,the clinical pathologic data complete;Compare the relationship between age groups of patients with prostate cancer detection rate,and the age groups of patients with Gleason grading and clinical staging for correlation analysis.Results Ⅰ,Ⅱ,Ⅲ,Ⅳ tumours positive rate was 11.63% (5/43),29.30% (46/ 157),30.28% (43/142),38.46% (10/26).Puncture positive rate are positively related with age,the prostate cancer detection rate comparison (Z =4.078,P 〈0.01).Ⅰ,Ⅱ,Ⅲ,Gleason score 7 or higher of patients Ⅳ group respectively,1 case (20%),11 cases (23.91%),30 cases (69.77%),7 cases (70%),there was no significant correlation with age (P =0.23).The Ⅰ,Ⅱ,Ⅲ,Ⅳ group in patients with localized prostate cancer respectively,3 cases(60%),32 cases(69.57%),33 cases(76.74%),4 cases(40%).Locally advanced prostate cancer respectively,1 case(20%),12 cases(26.09%),8 cases (18.60%),4 cases (40%).Advanced prostate cancer respectively,1 case (20%),2 cases (4.35 %),2 cases (4.65 %),2cases(20%).Each stage had no significant correlation with age(P =0.101 6,P =0.285 2,1 P =0.349).Conclusions Patients with PSA 4 ~ 10μg/L prostate cancer detection rate increased with age,tumor malignant degree and the transfer of risk and age has no obvious correlation.
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:3.17.70.182