振荡肺功能原理及技术实现  

Methodology and Implementation of Forced Oscillation Technique for Respiratory Mechanics Measurement

作　　者：张政波[1] 倪路 刘晓莉[2] 李德玉[2] 王卫东[1] 

机构地区：[1]解放军总医院医学工程保障中心,北京市100853 [2]北京航空航天大学生物与医学工程学院,北京市100191

出　　处：《中国医疗器械杂志》2015年第6期432-436,共5页Chinese Journal of Medical Instrumentation

基　　金：国家科技支撑计划课题(2013BAI03B05);国家自然科学基金面上项目(61471398)

摘　　要：强迫振荡技术是一种无创的呼吸系统力学特性测量技术。通过给呼吸系统施加高频激励信号（通常为4-40 Hz的振荡压力信号）,采用系统辨识原理,可实现不同频率、不同气道部位、不同阻力成分的阻抗特性的测量。该文综述了振荡肺功能基本原理、技术实现和临床应用,包括测量原理、激励信号、系统等效模型、辨识算法以及测量系统软硬件基本要求等,并对该技术的发展趋势作了展望。The forced oscilation technique （FOT） is a noninvasive method for respiratory mechanics measurement. For the FOT, external signals （e.g. forced oscilations around 4-40 Hz） are used to drive the respiratory system, and the mechanical characteristic of the respiratory system can be determined with the linear system identification theory. Thus, respiratory mechanical properties and components at different frequency and location of the airway can be explored by specificaly developed forcing waveforms. In this paper, the theory, methodology and clinical application of the FOT is reviewed, including measure ment theory, driving signals, models of respiratory system, algorithm for impedance identification, and requirement on apparatus. Finaly, the future development of this technique is also discussed.

关 键 词：强迫振荡技术 呼吸力学 系统辨识 压力-流量 脉冲振荡 

分 类 号：R318.6[医药卫生—生物医学工程]