瑞芬太尼复合丙泊酚靶控输注对脑肿瘤手术患者的麻醉效果  

Anesthesia effect discussing of Remifentanil and Propofol target controlled infusion in patients with brain tumor surgery

作　　者：周强[1] 

机构地区：[1]鞍山市肿瘤医院麻醉科,鞍山114000

出　　处：《中国当代医药》2015年第33期69-71,共3页China Modern Medicine

摘　　要：目的探讨在脑肿瘤患者手术中运用瑞芬太尼与丙泊酚复合麻醉方案的效果。方法随机将2012年1月-2015年1月到本院治疗的70例脑肿瘤患者分成两组,对照组35例采取芬太尼＋丙泊酚复合方案麻醉,观察组35例选择瑞芬太尼＋丙泊酚复合方案麻醉,研究两组的麻醉处理情况。结果两组各时点的平均动脉压（MAP）、T_0时点的心率（HR）比较接近,差异无统计学意义（P〉0.05）,观察组T_1-T_3时点的HR值较对照组明显降低,差异有统计学意义（P〈0.05）。观察组的术后睁眼与拔管时间较对照组更短,差异有统计学意义（P〈0.05）。两组麻醉期间均未见严重的肝肾异常。结论选择瑞芬太尼＋丙泊酚复合方案对脑肿瘤手术患者进行靶控输注,麻醉效果更加理想,更利于促进患者术后苏醒,适合临床推广。Objective To discuss the anesthesia effect of Remifentanil and Propofol target controlled infusion in patients with brain tumor surgery. Methods From January in 2012 to January in 2015,70 cases of brain tumors patients treated in our hospital were randomly divided into two groups.35 cases in the control group were narcotized with Fentanyl and Propofol,and 35 cases in the observation group were narcotized with Remifentanil and Propofol.Then the anesthesia treatment of two groups were studied. Results The MAP value of the two groups at each time point,and HR in T0 were nearly and had no statistical significance（P〉0.05）.The HR value at the T1-T3 time points of the observation group were significantly lower than those in the control group with statistical significances（P〈0.05）.The postoperative opening eye time and extubation time in the observation group were shorter than those in the control group with statistically significance（P〈0.05）.The severe abnormal condition of the liver and the kidney was not found in the two groups during anesthesia. Conclusion The anesthesia effect of Remifentanil and Propofol target controlled infusion in patients with brain tumor surgery is more ideal and more conducive to promote the revival of patients in postoperative time,and it is suited to promoting in clinic.

关 键 词：脑肿瘤手术 瑞芬太尼 丙泊酚 麻醉效果 

分 类 号：R739.41[医药卫生—肿瘤]