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机构地区:[1]北京市大兴区人民医院首都医科大学燕京医学院附属大兴医院内六科,北京102600 [2]河北医科大学第一医院放射科,河北石家庄053100
出 处:《中国医药导报》2015年第35期71-74,共4页China Medical Herald
基 金:河北省医学科学研究重点课题计划(20120277)
摘 要:目的探讨平阳霉素碘化油乳剂加明胶海绵颗粒在血管瘤介入栓塞治疗中的疗效。方法选取2011年1月~2014年1月的北京市大兴区人民医院收治的62例血管瘤患者,其中对照组30例,观察组32例。对照组使用平阳霉素碘化油乳剂栓塞的方法进行治疗,观察组使用平阳霉素碘化油乳剂加明胶海绵颗粒栓塞的方法进行治疗.比较两组患者临床疗效以及满意度情况。结果观察组有效率(96.9%)明显高于对照组(76.7%),差异有统计学意义(P〈0.05)。观察组患者满意度明显优于对照组,差异有统计学意义(P〈0.05)。观察组患者治疗前总胆汁酸水平为(13.24±3.20)μmol/L,对照组为(13.17±3.13)μmol/L,两组差异无统计学意义(P〉0.05);治疗后,观察组为(6.11±2.01)μmol/L,较对照组的(11.53±2.35)μmol/L明显降低,差异有统计学意义(P〈0.05)。观察组不良反应的发生率为37.5%。低于对照组的40.0%,但差异无统计学意义(P〉0.05)0结论平阳霉素碘化油乳剂加明胶海绵颗粒在介入治疗肝血管瘤中疗效显著,其疗效较仅使用平阳霉素碘化油乳剂更优。Objective To discuss the effect of Pingyangmyein-lipiodol emulsion combined with gelatin sponge in hepatic hemangioma thrombotherapy. Methods From January 2009 to January 2014, in People's Hospital of Daxing District, 62 patients with hepatic hemangioma were selected, and they were divided into: observation group (32 cases) were treated with Pingyangmycin-lipiodol emulsion and gelatin sponge, and control group (30 cases) were treated with Pingyangmycin-lipiodol emulsion. The therapeutic effect and satisfaction degree of two grouos were compared. Results The effective rate of observation group (96.9%) was lower than that in control group (76.7%), the difference was statistically significant (P 〈 0.05). The satisfaction degree in observation group was better than that in control group, the dif- ference was statistically significant (P 〈 0.05). Before treatment, the total serum TBA in observation group was (13.24±3.20) μ mol/L, and that in control group was (13.17±3.13) μmol/L, the difference was not statistically significant (P 〉 0.05); after treatment, the total serum TBA in observation group was (6.11±2.01) μmol/L, this was lower than that in control group [(11.53±2.35) μmol/L], the difference was statistically significant (P 〈 0.05). The incidence of complication in observation group was 37.5%, which was lower than that in control group (40.0%), but the difference was not statistically significant (P 〉 0.05). Conclusion Pingyangmycin-lipiodol emulsion combined with gelatin sponge has better clinical effect in treatment of hepatic hemangioma.
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