术前血清CEA联合β-HCG及CXs检测在非小细胞肺癌诊断中的价值  

Clinical significance of preoperative detection of serum CEA,β-HCG and CXs in diagnosis of non-small cell lung cancer

作　　者：杨显华[1] 陈娟[2] 

机构地区：[1]潜江市中心医院检验科,湖北潜江433100 [2]十堰市人民医院检验科,湖北十堰442000

出　　处：《海南医学院学报》2016年第1期79-81,85,共4页Journal of Hainan Medical University

基　　金：湖北省自然科学基金资助项目(c201315)~~

摘　　要：目的：对术前血清CEA联合β-HCG及CXs检测在非小细胞肺癌诊断中的临床价值进行研究，为I临床诊断与疾病治疗提供参考。方法：对本院2009年4月～2014年4月期间诊治的非小细胞肺癌患者进行分析，统计患者术前血清中CEA、β-HCG及Cxs与非小细胞肺癌临床分期及预后的相关性。以本院同期健康体检者为对照组。结果：血清中CEA、β-HCG及CXs与患者的年龄性别无明显相关性（P〉0．05），但CEA和β-HCG与非小细胞肺癌临床分期及预后呈负相关性，而Connexin43与非小细胞肺癌临床分期及预后呈正相关性。结论：术前血清CEA联合β-HCG及CXs检测可作为非小细胞肺癌临床诊断及预后的关键分子。Objective： To study the clinical significance of preoperative detection of serum CEA, β-HCG and CXs in the diagnosis of non-small cell lung cancer. Methods： Non-small cell lung cancer patients treated in our hospital from April 2009 to April 2014 were seletced. Correlation of preoperative serum CEA, β-HCG, Cxs with clinical stages as well as prognosis of nonsmall cell lung cancer was explored. Healthy subjects in our hospital during the same period were taken as control group. Resuits： Serum CEA, β-HCG and Cxs had no significant correlation with patients＇ age and gender （P〉0.05）, but CEA and β- HCG had negative correlation with the clinical stages and prognosis of non-small cell lung cancer while Connexin43 had positive correlation with the clinical stages and prognosis of non-small cell lung cancer. Conclusion： Preoperative serum CEA combined with β-HCG and CXs detection is the key in clinical diagnosis and prognosis of non-small cell lung cancer.

关 键 词：非小细胞肺癌 癌胚抗原 人绒毛膜促性腺激素 临床分期 诊断 预后 

分 类 号：R734.2[医药卫生—肿瘤]