改进手术方法对乳腺癌改良根治术后皮下积液的预防效果研究  

Effect of modified surgical method on subcutaneous hydrops of patients with breast cancer after modified radical mastectomy

作　　者：李琰 潘华锋 孙桂兰 

机构地区：[1]湖北省武汉市普仁医院甲乳外科,湖北武汉430081

出　　处：《海南医学院学报》2016年第2期175-177,181,共4页Journal of Hainan Medical University

基　　金：国家自然科学基金重点资助项目(2006-C030304)~~

摘　　要：目的:通过前瞻性临床随机研究,观察改进的手术方法对乳腺癌改良根治术后皮下积液的预防效果。方法:行乳腺癌改良根治术患者80例,随机分为2组:实验组40例和对照组40例,分别采用如下不同的手术方法,观察术后头3天的日引流量;至24h引流量≤20mL时拔除引流管,记录引流天数,发生皮下积液的例数以及所有手术后发生的不良事件。结果:实验组头3天内的每日引流量下降很快,且均相应地少于对照组,到第3天时不超过50mL/24h。实验组的引流总天数中位数(4d)少于对照组(7d)(P<0.01);实验组的皮下积液发生率仅为2%,大大低于对照组的14%(P<0.01),实验组引流管无1例被堵塞。结论:改进的手术方法,相比于传统手术方法,能显著减少积液的发生率,并且手术安全可靠,未见术后并发症增加。Objective： To observe the preventive effect of modified surgical method on subcutaneous hydrops of patients with breast cancer after modified radical mastectomy. Methods： A total of 80 patients of breast cancer scheduled for modified radical mastectomy were randomized into two groups by half. The daily drain volume was measured and recorded in the first 3 postoperative days. Drainage tube was removed when the volume was less than 20 mL in 24 h. The days of drainage, cases of seroma formation as well as any side effect were recorded. Results：The median drainage volume decreased very quickly in group 1, and the volume was less than group 2. It was 〈50 mL/24 h on day 3. Drainage tube were removed earlier in group 1 （me- dian time= 4 d） than those in group 2 （median time= 7 d） （P 〈0.01）. The incidence of subcutaneous hydrops of group 1 was 2%, significantly towe, r than group 2 （14%） （P 〈0.01）. No tube blocking occurred in group 1. Conclusions： Compared with traditional surgery, modified surgery can reduce incidence of subcutaneous hydrops, It is safe and is of few side effects.

关 键 词：乳腺癌 乳房切除术 皮下积液 腋窝清扫 

分 类 号：R737.9[医药卫生—肿瘤]