原发睾丸胚胎癌的诊断与治疗(附6例报告并文献复习)  

Diagnosis and treatment of primary testicular embryonal carcinoma(Report of six cases and literature review)

作　　者：陈少峰[1] 杨永姣 王尚任 龙安安 陈业刚[1] 郭战军[1] 王一[1] 孙光[1] 刘晓强[1] 

机构地区：[1]天津医科大学第二医院泌尿外科,天津市泌尿外科研究所,天津市泌尿外科基础医学重点实验室,天津300211

出　　处：《临床泌尿外科杂志》2015年第12期1080-1082,共3页Journal of Clinical Urology

摘　　要：目的：探讨睾丸胚胎癌临床、病理特点和诊疗方法。方法：回顾2005年-2015年我院收治的6例睾丸胚胎癌的临床资料,参考国内外胚胎癌病例报告并总结诊疗特点。结果：6例术后病理诊断均为胚胎癌,其中5例行睾丸根治性切除术后辅助化疗,1例行睾丸根治性切除术后辅助腹膜后淋巴结清扫及化疗等综合治疗,术后平均随访51（6-101）个月,未见复发及转移。结论：睾丸胚胎癌是一种较少见的男性恶性睾丸肿瘤,多数临床症状不明显,因睾丸肿块就诊,B超为首选检查,血清肿瘤标志物对诊断很重要。最终确诊需要依靠病理诊断,手术治疗是首选治疗方法,腹膜后淋巴结肿大者,需行腹膜后淋巴结清扫术,术后辅以辅助治疗效果更佳。Objective： To investigate clinicopathological characteristics, diagnosis and treatment of testicular embryonal carcinoma. Method： We retrospectively analyzed the clinical data of six cases of testicular emhryonal carcinoma in our hospital from 2005 to 2015 and reviewed the relevant literature. Result： The diagnosis of testicular embryonal carcinoma was confirmed by postoperative pathology. All six cases underwent operation and chemotherapy, and only one of them underwent retroperitoneal lymphadenectomy. No tumor recurrence and metastasis was found during the average follow-up period of 51 （range, 6-101） months. Conclusion： Testicular embryonal carcinoma is a rare carcinoma with atypical clinical manifestation, and the main symptom is testicular mass. Ultrasound is an optimal examination, and serum tumor markers are also helpful for diagnosis. The definite diagnosis is based exclusively on pathology. Surgical treatment is the first choice. Retroperitoneal lymphadenectomy should be undergone to the patients with retroperitoneal lymphadenectasis, and the prognosis will be better if chemotherapy participates in the comprehensive treatment.

关 键 词：胚胎癌 睾丸肿瘤 病理特点 诊治 

分 类 号：R737.21[医药卫生—肿瘤]