急性前葡萄膜炎黄斑中心凹下脉络膜厚度的改变  

Changes of subfoveal choroidal thickness in acute anterior uveitis

作　　者：郭春英[1] 乔丽君[1] 张婧[1] 高鹰[1] 杨柳[1] 

机构地区：[1]北京大学第一医院眼科,北京市100034

出　　处：《眼科新进展》2015年第12期1152-1154,共3页Recent Advances in Ophthalmology

摘　　要：目的分析急性前葡萄膜炎患者双眼黄斑中心凹下脉络膜厚度的变化。方法选取单眼首次发作的急性前葡萄膜炎患者16例(16眼),同时选取与之年龄、性别、屈光状态相匹配的无眼病及全身性疾病的正常人16例(16眼)作为对照组。利用海德堡HRA-Spectralis频域光学相干断层深度增强成像(enhanced depth imaging-spectral domain optical coherence tomography,EDI-OCT)测量急性前葡萄膜炎发作眼和对侧眼,以及正常对照眼的黄斑中心凹下脉络膜厚度。采用配对t检验检测结果的可靠性。结果急性前葡萄膜炎发作眼、对侧眼及正常对照眼的黄斑中心凹下的脉络膜厚度分别为(318.93±101.25)μm、(265.87±65.17)μm及(244.73±58.72)μm。发作眼和对侧眼之间的黄斑中心凹下脉络膜厚度差异有统计学意义(P=0.000),发作眼和对照眼之间差异也有统计学意义(P=0.000),而对侧眼和对照眼之间的黄斑中心凹下脉络膜厚度差异无统计学意义(P=0.290)。结论 EDI-OCT测量黄斑中心凹下脉络膜厚度为进一步加深对急性前葡萄膜炎的认识提供了有利的检测手段。Objective To investigate the changes of binocular subfoveal choroidal thickness（SFCT） in patients with acute anterior uveitis.Methods Sixteen first onset unilateral acute anterior uveitis patients（16 eyes） were selected.Another 16 age,gender and refractive statusmatched normal people without any ocular or systemic disease were enrolled in this study as control.SFCT was measured by Heidelberg HRA-Spectralis EDI-OCT in the onset eye,contralateral eye,as well as the control eye.Statistical analysis was conducted by paired t test.Results SFCT choroidal thickness of the onset eye of acute anterior uveitis was（318.93 ± 101.25） μm,the contralateral eye was（265.87±65.17） μm,and the control was（244.73 ± 58.72） μm.SFCT of the onset eye was significantly thicker than that of the contralateral eye（P = 0.000） and the control eye（P = 0.000）,but no significant difference was found between the contralateral eye and control eye（P = 0.290）.Conclusion EDI-OCT provides a favorable testing means to deepen our understanding of acute anterior uveitis by measuring SFCT.

关 键 词：急性前葡萄膜炎 脉络膜厚度 频域光学相干断层深度增强成像 

分 类 号：R773[医药卫生—眼科]