围术期输血对恶性肿瘤患者的影响  

Effects of perioperative blood transfusion on patients with malignant tumor

作　　者：刘新君[1] 

机构地区：[1]河南省安阳市肿瘤医院,455000

出　　处：《中国实用医刊》2015年第24期52-53,共2页Chinese Journal of Practical Medicine

摘　　要：目的 探究围术期输血对恶性肿瘤患者的影响.方法 选取安阳市肿瘤医院2012年6月至2014年9月收治的156例恶性肿瘤患者为研究对象,从输血方案出发将患者分为三组：A组29例行去白细胞血液输注,涵盖血浆、红细胞及冷沉淀、血小板,B组17例行自体输血,C组110例未做输血处理.观察三组免疫功能变化情况,并分析输血后不良反应发生情况及3、5年内转移复发、生存状况.结果 凝血功能变化：A组lgG、IgA[（9.14±0.35） g/Lvs （12.44±0.34） g/L,（2.10±0.31） g/L vs（2.67±0.30）g/L]均低于B组,差异有统计学意义（P＜0.05）.A组不良反应发生率、3年内转移复发率、5年内生存率分别为6.89％、31.03％、48.27％,B组分别为48.27％、48.27％、70.58％,C组分别为0、23.63％、66.36％,B、C组与A组比较差异有统计学意义（P＜0.05）.结论 针对恶性肿瘤患者而言,临床上严格把控输血指征,尽可能地采用血液替代品或自体输血,对提升输血质量、改善患者预后具有积极的应用意义,临床上需引起重视.Objective To investigate the effects of perioperative blood transfusion on patients with malignant tumor.Methods One hundred and fifty-six patients with malignant tumor from June 2012 to September 2014 were divided into three groups starting from the blood transfusion solution.Twenty-nine patients in group A were given leukocyte blood transfusion, covering plasma, red blood cells and cryoprecipitate, platelets;Seventeen patients in group B were given autologous blood transfusion;One hundred and ten patients in group C were not given transfusion, the changes of immune function in three groups were observed, then the occurrence of adverse reactions after blood transfusion and the metastasis and recurrence, survival status in 3, 5 years were analyzed.Results Coagulationchanges： lgG, IgA in group A were （9.14±0.35） g/L, （2.10 ±0.31） g/L respectively;lgG, IgA in group B were （12.44 ±0.34） g/L, （2.67 ± 0.30） g/L respectively, the former was lower than the latter, the differences were significant （P 〈 0.05）.The incidence of adverse reactions, the rate of metastasis and recurrence in 3 years, the survival rate in 5 years： group A were 6.89%, 31.03% and 48.27% respectively;group B were 48.27%, 48.27% and 70.58% respectively;group C were 0, 23.63% and 66.36% respectively, compared group B, C with group A, the differences were significant （P 〈 0.05）.Conclusions As for the patients with malignant tumor, strictly control the clinical blood transfusion syndrome, and use blood substitutes or autologous blood transfusion as far as possible, there is positive significance to enhancing the quality of blood transfusion and improving the prognosis of patients, and we should pay much attention to it in clinics.

关 键 词：围术期 输血 恶性肿瘤 影响 

分 类 号：R-05[医药卫生]