ABCD^2评分联合责任血管易损斑块对短暂性脑缺血发作后短期发生脑梗死的评估  

Value of combined ABCD^2 score and vulnerable plaques in predicting ischemic stroke shortly after TIA

作　　者：徐辉[1] 方岩[1] 张莹[1] 周海云[1] 王遂山[1] 

机构地区：[1]商丘市第一人民医院神经内科,476000

出　　处：《中华老年心脑血管病杂志》2015年第12期1298-1300,共3页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

摘　　要：目的探讨ABCD2评分联合责任血管易损斑块筛查对短暂性脑缺血发作(TIA)后短期内脑梗死的预测价值。方法选择TIA患者126例,以第7天为终点事件时间,将患者分为脑梗死组30例和非脑梗死组96例。根据ABCD2评分分为低危患者40例(0~3分)和中高危患者86例(4~7分)。应用彩色多普勒超声和(或)CT血管成像结果筛查责任血管,分为易损斑块患者79例和非易损斑块患者47例,比较脑梗死组与非脑梗死组之间危险因素和ABCD2评分,分析中高危人群(ABCD2评分≥4分)易损斑块在脑梗死组与非脑梗死组的差异。结果脑梗死组ABCD2评分≥4分和责任血管易损斑块比例明显高于非脑梗死组(46.7%vs 20.8%,90.0%vs 54.2%,P<0.01);当ABCD2评分≥4分时,易损斑块患者7d脑梗死发生率明显高于非易损斑块患者(83.3%vs 8.0%,P<0.01)。结论 ABCD2评分结合责任血管易损斑块筛查能提高短期内TIA患者脑梗死的预见风险。Objective To study the value of combined ABCD2 score and vulnerable plaques in predicting ischemic stroke shortly after TIA.Methods One hundred and twenty-six patients after TIA were divided into ischemic stroke group（n=30）and non ischemic stroke group（n=96）,further divided into low risk group with an ABCD2 score of 0-3（n=40）and high risk group with an ABCD2 score of 4-7（n=86）,vulnerable plaque group（n=79）and non vulnerable plaque group（n=47）.The risk factors and ABCD2 score were compared between ischemic stroke group and non ischemic stroke group.Vulnerable plaques in two groups with their ABCD2 score ≥4were analyzed.Results The proportion of vulnerable plaques was significantly higher in ischemic stroke group with its ABCD2 score≥4than in non ischemic stroke group（P0.01）.The incidence of ischemic stroke was significantly higher in vulnerable plaque group than in non vulnerable plaque group on day 7after TIA（P0.01）.Conclusion Comined ABCD2 score and vulnerable plaque can effectively predict the risk to develop ischemic stroke on day 7after TIA.

关 键 词：脑缺血发作 短暂性 脑梗死 诊断显像 磁共振成像 预测 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]