156名油田测井工人染色体畸变分析  

Chromosome aberration in 156 oil well logging workers

作　　者：谢国强[1] 麦维基[1] 陈铿铿[1] 孙杰[1] 张宗军[1] 李森华[1] 

机构地区：[1]广东省职业病防治院检验科,广东广州510300

出　　处：《实用预防医学》2016年第1期10-12,共3页Practical Preventive Medicine

基　　金：广东省医学科研基金资助项目(A2011047)

摘　　要：目的分析油田测井工人外周血淋巴细胞染色体畸变率。 方法 对156名某油田测井工人（放射组）和60名健康成人（对照组）进行人均年剂量当量和外周血淋巴细胞染色体畸变检测，并进行比较。 结果 （1）放射组染色体细胞畸变率（0．60％）、染色体型畸变率（0．28％），单体型畸变率（0．37％），无着丝粒断片发生率（0．56％）均显著高于对照组，差异有统计学意义（P〈0．05）；（2）放射工龄5-年组的“双＋环”畸变率（0．10％）高于放射工龄15年以上组（0．00％），差异有统计学意义（P〈0．05）；（3）中子人均年剂量当量0．20 mSv以上组的各类型畸变率最高，细胞畸变率（1．16％）、单体型畸变率（0．55％）、体型畸变率（0．61％）、“双＋环”畸变率（0．13％）、无着丝粒断片发生率（1．03％）均显著高于对照组，差异有统计学意义（P〈0．05）。 结论 油田测井工人外周血淋巴细胞染色体畸变率升高，而且中子人均年剂量当量较高的工人染色体各类型畸变率较高。Objective To analyze the chromosome aberration rates of peripheral blood lymphocytes among oil well loggingworkers. Methods One hundred and fifty- six oil well logging workers （the radiation group） and 60 healthy adults （the con-trol group） were chosen to observe and compare the annual dose equivalent per capita and chromosome aberration of peripheralblood lymphocytes. Results The incidences of chromosome celt aberration （0.60%）, chromosome- type aberration（0.28%） and chromatid - type aberration （0.37%） and acentrie fragment （0.56 % ） in the radiation group were all higher thanthose in the control group, with statistically significant differences （P 〈 0.05）. ＂Dicentric ＋ ring＂ aberration rate was higher inworkers with 5 - years radiation seniority （0.10%） than in ones with 15 - years radiation seniority （0.00%）, with statisticallysignificant differences （P 〈 0.05）. The workers exposed to annual neutron dose equivalent per capita -0.20 mSv had the high-est incidences of cell aberration （ 1.16% ）, chromatid - type aberration （ 0.55% ）, chromosome - type aberration （ 0.61% ）,＂Dicentric ＋ ring＂ （0.13 % ） and acentric fragment （1.03 % ）, which were all significantly higher than these of the controls （P 〈0.05）. Conclusions Oil well logging workers have higher incidence of chromosome aberration in peripheral blood lympho-cytes; moreover, the workers with higher annual dose equivalent per capita have higher chromosomal aberration frequencies.

关 键 词：油田测井工人 人均年剂量当量 染色体畸变 

分 类 号：R135.1[医药卫生—劳动卫生]