抑郁症患者的双眼竞争研究  

A study of binocular rivalry in patients with depression

作　　者：贾婷[1] 叶星[1] 魏强[1] 吴娇南 朱一鸣[1] 谢雯[2] 蔡春岚[2] 田仰华[1] 汪凯[1] 

机构地区：[1]安徽医科大学第一附属医院神经内科,合肥230022 [2]安徽省精神卫生中心

出　　处：《中华行为医学与脑科学杂志》2015年第11期986-988,共3页Chinese Journal of Behavioral Medicine and Brain Science

基　　金：国家自然科学基金项目（81401049,81471117）

摘　　要：目的 采用双眼竞争范式,探讨抑郁症患者的双眼竞争交替速率.方法 纳入35例抑郁症患者与30名性别构成、年龄、受教育程度相匹配的健康受试者,采用双眼竞争范式进行双眼竞争交替速率的检查.结果 患者组较对照组双眼竞争交替速率显著减慢[（0.27±0.06） Hz vs（0.43±0.11） Hz],且二者差异有统计学意义（t=-6.657,P＜0.001）.采用Pearson相关分析结果表明,抑郁组患者交替速率与其HAMD评分无明显相关性（r=-0.158,P=0.364）.结论 抑郁症患者双眼竞争交替速率较正常对照组显著减慢.抑郁情绪本身对抑郁症患者的交替速率无明显影响.Objective To investigate rivalry alternating rates in patients with depression using binocular rivalry paradigm.Methods Thirty-five patients with depression and 30 healthy controls matched for gender,age,education were recruited to assess the rivalry alternating rate using binocular rivalry test.Results The rivalry alternating rate of depression group was significantly slower than that of the control group （（0.27±0.06） Hz vs （0.43 ±0.11）Hz,t=-6.657,P〈0.001）.Pearson correlation analysis showed that there was no significant correlation between the rivalry alternation rates and HAMD scores in the patients with depression （r=-0.158,P=0.364）.Conclusion The binocular rivalry alternation rate of the patients with depression was significantly slower than that of the healthy controls.The depressed mood itself has no significant effect on binocular rivalry rate.

关 键 词：抑郁症 双眼竞争 血清素 

分 类 号：R749.4[医药卫生—神经病学与精神病学]