超选择性术前栓塞富血供大型脑膜瘤的疗效观察  

Curative observation of preoperative superselective embolization of large-hypervascular meningioma

作　　者：张智洲[1] 郭章[1] 陈海平[1] 方奕儒 

机构地区：[1]福建医科大学附属漳州市医院神经外科,漳州363000

出　　处：《中华神经医学杂志》2015年第12期1275-1277,共3页Chinese Journal of Neuromedicine

摘　　要：目的探讨应用Glubran2胶超选择性栓塞在富血供大型脑膜瘤手术切除中的作用。方法福建医科大学附属漳州市医院神经外科自2008年1月至2014年4月共收治富血供大型脑膜瘤患者16例，其中12例患者术前行数字减影血管造影fDSA）检查和超选择性肿瘤供血动脉栓塞（栓塞组），4例患者未行术前栓塞（未栓塞组）。回顾性分析患者的临床资料，观察栓塞组和未栓塞组患者的疗效。结果栓塞组患者DSA检查显示肿瘤100％栓塞4例、90％栓塞3例、75％栓塞5例。12例患者栓塞术后均无并发症发生。与非栓塞组患者比较，栓塞组患者的肿瘤全切率高（100％vs75％），术中出血量较少，手术时间较短。结论超选择性栓塞可明显减少富血供大型脑膜瘤术中出血、提高手术切除率及减少手术并发症。Objective To evaluate of preoperative embolization with Glubran 2 glue before surgical resection of large-hypervascular meningiomas （LHMs）. Methods Sixteen patients, admitted to our hospital from January 2008 to April 2014, were selected in our study; 12 of them were performed preoperative DSA and embolization with Glubran 2 glue （embolization group） and 4 of them did not accept embolization （non-embolization group）; retrospective analysis of the clinical data and treatment efficacy of the two groups was performed. Results DSA showed that the blood fed to tumors were completely blocked （100%） in 4 patients, and great partly （90%） in 3 and partly （75%） in 5 patients of the embolization group. Postoperative complications were not noted in the patients of embolization group. As compared with those in the non-embolization group, the total tumor removal rate （100% vs. 75%） was significantly higher in the embolization group, and the intra-operative bleeding was obviously reduced, and the operation time was greatly shortened in the embolization group. Conclusion Preoperative transarteial embolization of meningiomas can reduce intra-operative bleeding, improve operation safety and total tumor resection.

关 键 词：术前栓塞 富血供大型脑膜瘤 Glubran 2胶 

分 类 号：R739.45[医药卫生—肿瘤]