不同角膜温度下人眼前房热传递的数值模拟  

Numerical Simulation of Heat Transfer in the Human Anterior Chamber at Different Corneal Temperatures

作　　者：郭竞敏 张虹[1] 王军明[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院眼科,武汉430032

出　　处：《生物医学工程学杂志》2015年第6期1191-1195,共5页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(81470632)

摘　　要：重建人眼前房三维模型,探究不同角膜温度对前房热传递过程的影响。基于正常志愿者的光学相干断层扫描影像,采用UG参数化造型的方法对人眼前房进行三维建模,并用有限体积分析方法对不同角膜温度下整个前节的热传递和房水流动过程进行数值模拟。结果显示角膜温度对前房热传递和房水流动有显著影响:前房温度呈线性分布,沿瞳孔轴对称,温差越大则对称性越差;房水在低温侧上浮,在高温侧下沉,呈涡流样流动,温差越大则流速越快;角膜、晶体和虹膜的热通量主要受房水流速影响,流速越快则上述壁面热通量绝对值越大。基于光学相干断层扫描影像的人眼前房数值模拟切实可行,研究结果有助于深入认识角膜温度差异在前房热传递和房水动力学中的重要作用。A three-dimensional （3D） model of human anterior chamber is reconstructed to explore the effect of differ- ent corneal temperatures on the heat transfer in the chamber. Based on the optical coherence tomography imaging of the volunteers with normal anterior chamber, a 3D anterior chamber model was reconstructed by the method of UG parametric design. Numerical simulation of heat transfer and aqueous humor flow in the whole anterior chamber were analyzed by the finite volume methods at different corneal temperatures. The results showed that different corneal temperatures had obvious influence on the temperature distribution and the aqueous flow in the anterior chamber. The temperature distribution is linear and axial symmetrical around the pupillary axis. As the temperature difference increases, the symmetry becomes poorer. Aqueous floated along the warm side and sank along the cool side which forms a vortexing flow. Its velocity increased with the addition of temperature difference. Heat fluxes of cornea, lens andiris were mainly affected by the aqueous velocity. The higher the velocity, the bigger more absolute value of the above-mentioned heat fluxes became. It is practicable to perform the numerical simulation of anterior chamber by the optical coherence tomography imaging. The results are useful for studying the important effect of corneal tempera- ture on the heat transfer and aqueous humor dynamics in the anterior chamber.

关 键 词：光学相干断层扫描 前房 热传递 数值模拟 三维重建 

分 类 号：R779.6[医药卫生—眼科]