鼻咽癌自动调强放疗计划设计的可行性  

Feasibility of Automatic Treatment Planning in Intensity-modulated Radiotherapy of Nasopharyngeal Carcinoma

作　　者：何垠波[1] 张隆彬 肖江洪[1] 段宝凤[1] 

机构地区：[1]四川大学华西医院肿瘤中心,肿瘤放射物理技术中心,成都610041 [2]重庆三峡中心医院,重庆404100

出　　处：《生物医学工程学杂志》2015年第6期1288-1293,共6页Journal of Biomedical Engineering

摘　　要：鼻咽癌调强放疗计划十分复杂,计划质量通常与治疗剂量师的经验密切相关。本研究纳入了10例不同分期的鼻咽癌患者,基于Pinnacle3 9.2治疗计划系统脚本,运用计算机程序设置计划的基本参数、目标参数等,最终自动完成鼻咽癌调强放疗计划。然后,对自动和手动调强放疗计划进行统计学比较和临床评估。结果显示两种计划中大多数靶区和危及器官剂量学参数的差异无统计学意义。本文所述的鼻咽癌自动调强放疗计划能够满足临床放疗要求,显著减少计划时间,同时避免因为经验不足等人为因素对计划质量造成的影响。Intensity-modulated radiotherapy planning for nasopharyngeal carcinoma is very complex. The quality of plan is often closely linked to the experience of the treatment planner. In this study, 10 nasopharyngeal carcinoma patients at different stages were enrolled. Based on the scripting of Pinnacle3 9.2 treatment planning system, the computer program was used to set the basic parameters and objective parameters of the plans. At last, the nasopha- ryngeal carcinoma intensity-modulated radiotherapy plans were completed automatically. Then, the automatical and manual intensity-modulated radiotherapy plans were statistically compared and clinically evaluated. The results showed that there were no significant differences between those two kinds of plans with respect to the dosimetry pa- rameters of most targets and organs at risk. The automatical nasopharyngeal carcinoma intensity-modulated radio- therapy plans can meet the requirements of clinical radiotherapy, significantly reduce planning time, and avoid the in- fluence of human factors such as lack of experience to the quality of plan.

关 键 词：鼻咽癌 调强放射治疗 自动计划 

分 类 号：R739.63[医药卫生—肿瘤]