高分辨磁共振探讨大脑中动脉斑块形态和强化程度与脑梗死的关系  

The correlation between middle cerebral artery plaque morphology and enhancement degree and cerebral infarction by high resolution MRI

作　　者：孙雪园 张红梅[1] 牛琰鑫[1] 陈新[1] 

机构地区：[1]第二炮兵总医院医学影像科,北京100088

出　　处：《中国临床医学影像杂志》2015年第12期837-840,共4页Journal of China Clinic Medical Imaging

摘　　要：目的:应用3.0T高场和高分辨率磁共振成像技术检查有症状的颅内大脑中动脉粥样硬化性斑块是否存在、形态及斑块增强度,评估斑块稳定性与脑梗死发生的关系。材料和方法:回顾性分析60例动脉粥样硬化性大脑中动脉的成像和临床数据,高分辨率T_1WI显示斑块形态并测量斑块增强度和垂体增强度,两者之间比较分为3组:明显强化、轻度强化和无强化。结果:60例有症状的患者纳入统计,45例为偏心性斑块,研究19例急性期、14例亚急性期、15例慢性期和12例无脑梗死病灶的大脑中动脉斑块增强度,斑块增强度与垂体增强度间斯皮尔曼相关系数及P值有统计学意义。结论:大脑中动脉粥样硬化性斑块呈偏心性比较常见,斑块强化程度与斑块稳定性、脑梗死发生率之间有密切的关系,这两点相结合可用于与其他血管性病变相鉴别。Objective： To evaluate the presence, shape and enhancement degree of symptomatic middle cerebral artery atherosclerotic plaques by 3.0T high-field and high-resolution magnetic resonance imaging technology, and to evaluate the re- lationship between the stability of plaque and cerebral infarction. Methods： The imaging and clinical data of 60 cases of atherosclerotic middle cerebral artery were analyzed retrospectively, HR-T1WI shows plaque morphology and enhancement de- gree between plaque and pituitary, and the comparison between plaque and pituitary divided into three groups： strong en- hancement, mild enhancement and no enhancement. Result： Sixty cases of symptomatic patients were included in the statistics, and 45 cases had eccentric plaques. The enhancement degree of middle cerebral artery plaque in 19 cases of acute phase, 14 cases of subacute phase, 15 cases of chronic phase and 12 cases without cerebral lesion were analyzed. The Spearman corre- lation coefficients between enhancement degree of plaque and enhancement degree of pituitary and P values were statistically significant. Conclusion： Middle cerebral artery eccentric atherosclerotic plaques are more common, and there is a close rela- tionship between the stability of plaque and the incidence of cerebral infarction, and the combination can be used to identify other vascular diseases.

关 键 词：梗塞 大脑中动脉 大脑中动脉 磁共振成像 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]