左、右后溪穴激活脑功能区相关性fMRI比较研究  

A f MRI Comparative Study of the Correlation of Left and Right Points Houxi(SI3) with Activated Brain Function Areas

作　　者：胡霞[1] 王华[2] 李佳[2,3] 刘建民[2] 吴松[2] 唐宏图[2,3] 徐海波[4] 韩俊洲[4] 

机构地区：[1]湖北中医药大学基础医学院,武汉430065 [2]湖北中医药大学/针灸治未病湖北省协同创新中心,武汉430065 [3]香港科技大学电子与计算机工程学系 [4]华中科技大学同济医学院附属协和医院,武汉430000

出　　处：《上海针灸杂志》2015年第12期1234-1238,共5页Shanghai Journal of Acupuncture and Moxibustion

基　　金：国家自然科学基金项目(90209031)

摘　　要：目的观察电针刺激周围性面瘫患者后溪穴在患者脑功能区的激活相关性,比较左、右侧后溪穴在成像上是否存在差异,并与电针合谷穴做比较。方法筛选左、右侧周围性面瘫患者各6例为研究对象,电针刺激,同时行全脑f MRI扫描,SPM软件进行图像后处理,t检验(P<0.01)分析得出电针不同穴位的脑功能图像。结果电针左侧后溪穴,右侧尾状核头、右侧扣带回、右侧海马回、右侧颞上回、脑干、小脑蚓等脑区信号升高;电针右侧后溪穴,右侧额内侧回、左侧额中回、左侧扣带回前部、右侧扣带回、右侧颞上回等脑区信号升高。结论电针后溪穴与合谷穴、地仓穴的成像存在差异,同时两侧后溪穴成像也存在较大差异,信号升高或降低的脑区并不一致。进一步证明了"面口合谷收"的科学性,也说明同名的穴位也许在人体的两侧存在一定的差异,比如传导通路的不完全相同,治疗作用的不完全一致等。Objective To investigate the correlation between electro-acupunctured point Houxi（SI3） and activated brain function areas, contrast the images produced with electroacupuncture at left and right points Houxi and make a comparison with electroacupuncture at point Hegu（LI4） in patients with peripheral facial paralysis. Method Patients with peripheral facial paralysis, six on the left side and six on the right side, were enrolled as subjects. A scan of the whole brain was taken using f MRI during electroacupuncture stimulation. The images were processed using SPM software. An analysis using a t-test（P〈0.01） showed differences in brain functional images produced with electroacupuncture at different points. Result Electroacupuncture at left point Houxi increased the signals of brain regions： right caudate nucleus, right cingulate gyrus, right parahippocampal gyrus, right superior temporal gyrus, the brainstem and the cerebellar vermis. Electroacupuncture at right point Houxi increased the signals of brain regions： right medial frontal gyrus, left middle frontal gyrus, left anterior cingulate gyrus, right cingulate gyrus and right superior temporal gyrus. Conclusion There is a difference in the image between electroacupuncture at point Houxi and at point Hegu or Dicang（ST4）. There is also a larger difference in the image between bilateral points Houxi. The brain regions with high-frequency or low-frequency signals are not consistent. The results further prove the scientificalness of ＂Point Hegu is indicated for diseases in the face and mouth＂ and also show that the cognominal acupoints on the two sides of the human body may have some differences, e.g. the conduction pathways are not completely the same and the therapeutic effects are not completely consistent.

关 键 词：磁共振成像 面神经麻痹 电针 穴 后溪 

分 类 号：R224[医药卫生—中医基础理论]