男性缺陷型精神分裂症患者面孔情绪认知与述情障碍的对照研究  

Facial emotion recognition and alexithymia in male patients with deficit schizophrenia:a case control study

作　　者：叶飞[1] 唐小伟[1] 沙维伟[1] 张晓斌[1] 

机构地区：[1]扬州大学医学院附属五台山医院,225003

出　　处：《临床精神医学杂志》2015年第6期373-376,共4页Journal of Clinical Psychiatry

基　　金：扬州市科技发展计划-社会发展项目(YZ2014215);扬州市自然科学基金(YZ2014025);江苏省卫生和计划生育委员会指导性科研课题(Z201522)

摘　　要：目的:探讨男性缺陷型精神分裂症(DS)和非缺陷型精神分裂症(NDS)患者面孔情绪认知缺陷和述情障碍以及与临床症状的相关性。方法:采用简明精神病评定量表(BPRS)、阴性症状量表(SANS)、阳性症状量表(SAPS)评定DS患者(DS组37例)和NDS患者(NDS组57例)的精神症状;使用中国人面孔情绪测验(CFET)和多伦多述情障碍量表-20(TAS-20)评估DS组、NDS组和招募的54名健康人(正常对照组)面孔情绪认知缺陷和述情障碍并进行比较。结果:相比正常对照组,DS组和NDS组显示出更严重的面孔情绪认知损害(除NDS组对喜的面孔识别以外)和更高的述情障碍成绩。DS组对恐的识别正确数、CFET总成绩与TAS-20因子3(外向性思维)呈负相关(恐:r=-0.339,P=0.038;CFET总成绩:r=-0.324,P=0.047);DS组中TAS-20总成绩与BPRS阴性症状分和SANS评分呈正相关(BPRS:r=0.455,P=0.005;SANS:r=0.339,P=0.043);相反,NDS组TAS-20总成绩/因子分与精神症状(BPRS、SAPS及SANS)无相关性。结论:DS和NDS存在不同的面孔情绪认知损害模式,述情障碍与DS阴性症状有关。Objective：To explore investigated facial emotion recognition deficits and alexithymia in deficit schizophrenia（ DS） and nondeficit schizophrenia（ NDS） patients and their relationships with other clinical variables.Method：The psychiatric symptoms of DS（ n = 37） and NDS（ n = 57） patients were evaluated with the brief psychiatric rating scale（ BPRS）,scale for the assessment of negative symptoms（ SANS）,and scale for the assessment of positive symptoms（ SAPS）.Facial emotion recognition deficits and alexithymia were assessed in DS,NDS,and 54 recruited healthy male（ control group） by the Chinese facial emotion test（ CFET） and the Toronto alexithymia scale-20（ TAS-20）.Results：Compared with control group,patients exhibited more severe facial emotion recognition impairments,with the exception of happy faces in NDS patients,as well as higher alexithymia scores.in DS patients,correct frequency for fear recognition and total CFET score were negatively correlated with TAS-20 factor 3 subscore for externally oriented thinking（ fear：r =-0.339,P = 0.038;total CFET：r =-0.324,P = 0.047）.Total TAS-20 score was positively correlated with BPRS negative symptom and SANS score in DS patients（ BPRS：r = 0.455,P = 0.005;SANS：r = 0.339,P = 0.043）.In contrast,there were no correlations between TAS-20 scores / subscores and psychiatric symptoms（ BPRS,SAPS and SANS） in NDS patients.Conclusion：These findings indicated distinct facial emotion recognition impairments in DS and NDS patients.Alexithymia might be specifically related to the negative symptom in DS patients.

关 键 词：缺陷型精神分裂症 面孔情绪认知 述情障碍 

分 类 号：R749.3[医药卫生—神经病学与精神病学]