颈内动脉严重狭窄或闭塞对脑梗死模式的影响  

The Effect of Internal Carotid Artery Severe Stenosis or Obstruction on Cerebral Infarction model

作　　者：张晶晶[1] 刘丽[1] 董志军[1] 白雪[1] 

机构地区：[1]赤峰市医院神经内科,内蒙古赤峰024000

出　　处：《内蒙古医学杂志》2015年第9期1029-1032,共4页Inner Mongolia Medical Journal

摘　　要：目的探索颈内动脉病变程度、部位、数量及斑块形态与脑梗死模式的关系。方法回顾性分析我院神经内科2012年6月至2015年1月份收住伴有颈内动脉≥70%狭窄或闭塞的缺血性脑梗死患者的临床资料,分为狭窄组和闭塞组,颅外病变组和颅内病变组,单侧病变和双侧病变组,稳定斑块组和不稳定斑块组,比较各组间梗死模式构成比差异性。结果共105名患者入组,颈内动脉狭窄重度狭窄患者75人(71.4%),闭塞患者30人(28.6%);颈内动脉颅外段病变患者80人(76.2%),颅内病变25人(23.8%);单侧颈动脉病变患者65人(61.9%),双侧病变患者40人(38.1%),稳定斑块患者22人(29.3%),不稳定斑块55人(70.7%)。颈内动脉闭塞与狭窄患者间、颅内病变与颅外病变患者间以及稳定斑块患者与不稳定斑块患者间梗死模式不同,差异有统计学意义;双侧颈内动脉病变与单侧病变患者间梗死模式构成比无统计学差异。结论颈动脉重度狭窄或闭塞时,颈动脉病变程度及部位、病变处斑块稳定性对于脑梗死模式有着明显影响,颈动脉病变数量对于梗死模式的影响不明显。Objective To explore the relation among classification,site,quantity of internal carotid artery（ICA）lesions,plaque morphology and cerebral infarction model.Method We retrospectively review the clinical information of acute cerebral infarction patients who admitted in our department due to ICA ≥50% stenosis or obstruction from june 2012 to January 2015.Patients were devided into stenosis group and obstruction group,extracranial group and intracranial group,unilateral group and bilateral group,stable plaque group and unstable plaque group.The differrences of infarction model constituent ratio among groups were compared.Results 105 eligible cases were enrolled.There were 75 patients（71.4%）in stenosis group and 30 patients（28.6%）in obstruction group,80 patients（76.2%）in extracranial group and 25patients（23.8%）in intracranial group,65 patients（61.9%）in unilateral group and 40 patients（38.1%）in bilateral group,22 patients（29.3%）in stable plaque group and 55 patients（29.3%）in unstable plaque group.The infarction models were different among stenosis and obstruction group,extracranial group and intracranial group,stable plaque group and unstable plaque group,stastical diffences were found;There were no stastical difference of infarction model constituent ratio between bilatera and unilateral groups.Conclusion When patients have ICA severe stenosis or obstruction,the classification and site of ICA lesions,stability of plaque have effects on cerebral infarction model,the quanlity of ICA lesions didn＇t have effect on cerebral infarction mode.

关 键 词：颈内动脉狭窄 梗死模式 斑块 病变部位 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R543.4[医药卫生—临床医学]