电针联合舍曲林治疗创伤后应激障碍的效果观察  

Effects of electric acupuncture combined with sertraline in the treatment of post-traumatic stress disorder

作　　者：周平[1] 张瑶[1] 谭庆荣[1] 

机构地区：[1]第四军医大学西京医院,西安710032

出　　处：《四川精神卫生》2015年第6期504-507,共4页Sichuan Mental Health

基　　金：国家自然科学基金资助项目(30870886)

摘　　要：目的观察电针联合舍曲林对创伤后应激障碍(PTSD)的疗效及安全性。方法将50例PTSD患者随机分为研究组(舍曲林联合电针治疗)和对照组(舍曲林治疗)各25例,均治疗4周。于治疗前和治疗4周末采用创伤后应激障碍检查表(PCL)及汉密尔顿焦虑量表(HAMA)评定疗效。结果共47位患者完成研究,两组治疗4周末PCL总评分、重现、回避、高警觉、HAMA评分均较治疗前低,差异有统计学意义(P<0.05);研究组治疗4周末PCL总评分、重现、高警觉、HAMA评分低于对照组,差异有统计学意义(P<0.05)。结论在舍曲林基础上联用电针治疗,能够增加舍曲林对PTSD的重现、高警觉核心症状和焦虑症状的疗效。Objective To observe the effects and safety of electric acupuncture combined with sertraline in the treatment of post- traumatic stress disorder(PTSD). Methods 50 patients with post - traumatic stress disorder were randomly divided into the com-bined group and the control group. Patients in combined group were treated with sertraline and electric acupuncture(30 min/ day, 5 days per week). Patients in control group were only treated with sertraline. Two groups were treated for 4 weeks. Before and after the treatment,the patients were tested by the PTSD Checklist(PCL)and Hamilton Anxiety Scale(HAMA). Results After 4 weeks’ treatment,the PCL total score,reproduce scores,avoidance scores,hyperarousal scores and HAMA scores were lower than before treatment in two groups,and the differences were statistically significant(P < 0. 05). The PCL total score,reproduce scores,hyperar-ousal scores and HAMA scores of the combined group decreased more obviously than the control group,and the difference was statisti-cally significant(P < 0. 05). Conclusion Electric acupuncture combined with sertraline can increase the effect of treatment in repro-duce hyperarousal and anxiety symptoms in PTSD.

关 键 词：电针 舍曲林 创伤后应激障碍 

分 类 号：R749.4[医药卫生—神经病学与精神病学]