121例直肠癌患者生存质量的影响因素研究  

Research of influence factors on the quality of life of 121 patients with rectal cancer

作　　者：郭俊伟[1] 瞿伟[1] 宋娟[2] 唐倩影[1] 谷珊珊[1] 罗菡[1] 

机构地区：[1]第三军医大学西南医院临床心理科,重庆400038 [2]第三军医大学西南医院普外科,重庆400038

出　　处：《四川精神卫生》2015年第6期511-515,共5页Sichuan Mental Health

摘　　要：目的探讨影响直肠癌患者生存质量的相关因素。方法选择重庆某三甲医院普外科2013年12月-2014年12月住院的直肠癌患者121例,并进行生存质量问卷(QLQ-30)、汉密尔顿抑郁量表(HAMD)和汉密尔顿焦虑量表(HAMA)评定。结果符合抑郁障碍诊断标准的有42例,抑郁检出率为34.71%;符合《国际疾病分类(第10版)》(ICD-10)焦虑障碍诊断的有38例,焦虑检出率31.40%。多元回归分析结果表明,患者生存质量受性别(P<0.05)、是否首诊(P<0.05)、家庭收入(P<0.05)、抑郁(P<0.05)、焦虑(P<0.05)等因素的影响。对整体生活质量(GQL)影响明显的因素有:年龄、家庭收入、是否知情;影响躯体功能(PF)的有:恶心呕吐、疲乏、是否首诊、HAMD总评分;恶心呕吐、疲乏、疼痛对角色功能(RF)有影响;性别、受教育程度对认知功能(CF)影响明显;HAMA、HAMD总评分、疼痛、食欲对情绪功能(EF)有影响;影响社会功能(SF)的因素有疲乏、性别、家庭收入。结论影响直肠癌患者生存质量的有多种因素,其中焦虑、抑郁等显著影响了直肠癌患者的生存质量,性别、是否首诊、经济收入也是影响患者生存质量的重要因素。Objective To explore the relative factors about the quality of life in patients with rectal cancer. Methods Quality of Life Questionnaire(QLQ - 30),Hamilton Depression Scale(HAMD)and Hamilton Anxiety Scale(HAMA)were used to evaluate 121 cases of patients with rectal cancer. Results A total of 42 patients(34. 71% )with depressive disorder and 38 patients(31. 40% )with anxiety disorder were detected according to ICD - 10. Multivariate regressionanalysis showed that patientsˊ quality of life were influ-enced by gender(P < 0. 05),whether the first contact(P < 0. 05),household income(P < 0. 05),depression(P < 0. 05)and anxiety (P < 0. 05). The factors which influenced the global quality of life(GQL)included:age,household income and whether informed. The factors influenced the physical function(PF)included:nausea and vomiting,fatigue,whether the first contact,the HAMD total score. Role function(RF)was affected by nausea and vomiting,fatigue,pain;cognitive function(CF)was influenced by gender and level of education;mood function(EF)was affectedby HAMA and HAMD total scores,pain,appetite;social function(SF)was in-fluenced by fatigue,gender,household income. Conclusion The quality of life of patients with rectal cancer are influenced by many factors,including mood disorders,such as depression and anxiety,gender,whether the first contact,household income.

关 键 词：直肠癌 生存质量 影响因素 

分 类 号：R[医药卫生]