I^(125)粒子植入治疗手术和放化疗后复发转移直肠癌的疗效探析  

Recurrence and Metastasis of Rectal Cancer after Implantation of I^(125) Particles and Chemotherapy

作　　者：郑丹 袁志平[2] 林川[2] 李晓明 王立帅[2] 王秋[2] 

机构地区：[1]四川医科大学附属第一医院,四川泸州646000 [2]宜宾市第二人民医院,四川宜宾644000

出　　处：《深圳中西医结合杂志》2015年第22期6-7,共2页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的:探讨I^(125)粒子植入治疗直肠癌根治术后放化疗后盆腔照射野内复发或伴远处转移患者的疗效。方法:对直肠癌根治性术后复发转移的部分患者给予I^(125)粒子植入治疗。结果:治疗2个月后粒子植入组患者疼痛程度较治疗前明显减轻(P<0.01)。治疗6个月后粒子植入组盆腔肿瘤缓解率、3年总体生存率比较,差异具有统计学意义(P<0.05)。结论:盆腔种植放射性粒子放疗可提高直肠癌术后放射野内复发患者生活质量,降低并发症发生风险。Objective To study the ^125 I particles embedded technology in the treatment of rectal cancer after radical postoperative chemoradiotherapy pelvic radiation field the curative effect of patients with recurrence or distant metastasis. MethodsFor the post-operation relapse and metastasis of colorectal cancer radical treatment with an implanted ^125 I particles in some patients. Results After treatment for 2 months before degree of particle implantation patients pain treatment significantly decrease（P〈0.01）. 6 months after treatment implanted group of pelvic tumor response rate, significant difference was found in 3 year overall survival rate. Conclusion Pelvic planting radioactive particle radiation therapy can improve the patients with rectal cancer recurrence of postoperative radiation field in the quality of life, reduce the risk of complications.

关 键 词：I^125放射性粒子 直肠癌 肿瘤根治术 肿瘤复发 

分 类 号：R735.37[医药卫生—肿瘤]