头孢哌酮/舒巴坦联合氨溴索治疗支气管扩张合并感染的临床疗效观察  

Observation of Cefoperazone/Sulbactam Combined With Ambroxol Treatment of Bronchiectasis With Infection

作　　者：任媛媛[1] 沈健伟[1] 李春娣[1] 李丽娜[1] 杨永山[1] 鹿爱平[1] 

机构地区：[1]大庆市人民医院,163316

出　　处：《中国继续医学教育》2015年第32期164-165,共2页China Continuing Medical Education

摘　　要：目的观察头孢哌酮/舒巴坦联合氨溴索治疗支气管扩张合并肺部感染的临床疗效。方法本次研究共纳入61例研究对象,均于我院就诊的支气管扩张合并感染患者。对照组30例患者采用环丙沙星抗感染,生理盐水肺泡灌洗;观察组31例采用头孢哌酮/舒巴坦抗感染、氨溴索配制液行肺泡灌洗。结果与对照组治疗10 d后相比,观察组超敏C反应蛋白较低,第1 s用力呼气量和最大呼气流量较高,临床疗效更好,差异均有统计学意义(P<0.05)。结论头孢哌酮/舒巴坦联合氨溴索可有效改善患者肺功能,控制感染,提高临床疗效。Objective To observe the effect of cefoperazone/ sulbactam combined with ambroxol in the treatment of bronchiectasis with pulmonary infection. Methods This study included 61 cases with bronchial dilatation and infection in our hospital. The control group of 30 cases were treated with anti-infection of ciprofloxacin, physiological saline lavage, observation group of 31 cases with cefoperazone/sulbactam anti infection, ambroxol hydrochloride preparation liquid underwent bronchoalveolar lavage. Results To compared with the control group, 10 d after treatment, sensitive C reactive protein in observation group was lower, the first second forced expiratory volume and maximum expiratory flow were higher than control group, the clinical efficacy was remarkable, the difference was statistically significant（P〈0.05）. Conclusion Cefoperazone/sulbactam combined with ambroxol can effectively improve the pulmonary function of patients, control of infection, improve the clinical efficacy.

关 键 词：头孢哌酮/舒巴坦 氨溴索 支气管扩张 感染 

分 类 号：R734.2[医药卫生—肿瘤]