成年体检人群幽门螺杆菌感染的相关因素  

Identification of factors related with Helicobacter pylori infection in adults

作　　者：郑奕[1] 

机构地区：[1]广西壮族自治区南溪山医院消化内科,广西壮族自治区桂林市541002

出　　处：《世界华人消化杂志》2015年第33期5412-5416,共5页World Chinese Journal of Digestology

摘　　要：目的:探究成年体检人群中幽门螺杆菌(Helicobacter pylori,H.pylori)感染的相关因素.方法:回顾性研究2008-01/2014-01在广西壮族自治区南溪山医院进行体检的10000例成年人群的相关资料,比较成年体检人群中年龄、性别、生活习惯、胃镜下不同病变等情况对H.pylori感染率的影响.结果:成年体检人群中男性和女性以及各年龄范围的总体差异均不显著(P>0.05),18-25岁的成人体检人群H.pylori感染的检查率最低,46-55岁的成人体检人群H.pylori感染的检出率最高.成年体检人群的高盐饮食、喜食甜食、常饮不洁水源、本人胃病史、家属胃病史等生活习惯与其H.pylori感染相关性较明显(P<0.05),而成年体检人群喜食熏制食物、常食生蔬菜、三餐不规律等生活习惯与其H.pylori感染相关性不明显(P>0.05);反流性食管炎的H.p y l o r i感染率明显低于正常食管(P<0.05),慢性萎缩性胃炎伴急性炎、胃溃疡、慢性萎缩性胃炎H.pylori感染率明显高于正常胃黏膜(P<0.05),十二指肠溃疡、十二指肠炎H.pylori感染率明显高于正常十二指肠(P<0.05).结论:成年体检人群中年龄和性别与H.pylori感染的相关程度较低,而成年体检人群H.pylori感染与其不良生活习惯和胃镜下的不同病变相关程度较高.AIM：To identify factors related with Helicobacter pylori（H.pylori） infection in the adult population.METHODS：A total of 10000 adults who underwent physical examination at our hospital from January 2008 to January 2014 were retrospectively studied.The impact of clinical data for these patients such as age,sex,lifestyle,and different endoscopic lesions on H.pylori infection was investigated.RESULTS：There was no significant difference in the distribution of gender or age group in the whole population（P〈0.05）.The 18-25 age group had the lowest rate of H.pylori infection,while the 46-55 age group had the highest rate.High-salt diet,eating sweet food,frequent drinking of unclean water,history of gastric disease,and family history of gastric disease were significantly associated with H.pylori infection（P〈0.05）,but eating smoked food,eating raw vegetables,irregular meals and other living habits had no obvious correlation with H.pylori infection（P〈0.05）.H.pylori infection rate was significantly lower in reflux esophagitis than in the normal esophagus（P〈0.05）.H.pylori infection rate was significantly higher in chronic atrophic inflammation associated with acute gastritis,gastric ulcer,and chronic atrophic gastritis than in the normal gastric mucosa（P〈0.05）,and in duodenal ulcer and duodenitis than in the normal duodenum（P〈0.05）.CONCLUSION：Age and gender have a low degree of correlation with H.pylori infection in adults,while higher H.pylori infection rate is associated with bad habits and different endoscopic lesions.

关 键 词：成人体检人群 幽门螺杆菌感染 14C尿素呼气试验 相关因素 

分 类 号：R57[医药卫生—消化系统]