MTA和Ca(OH)_2用于年轻恒牙活髓切断术疗效的系统评价  

Efficacy of MTA versus Ca(OH)_2 Applied for Immature Permanent Teeth Pulpotomy:A Systematic Review

作　　者：周海燕[1] 潘央央[1] 夏可可[1] 梅丽琴[1] 

机构地区：[1]温州医科大学附属口腔医院儿童口腔科,浙江温州325027

出　　处：《口腔医学研究》2015年第12期1223-1227,共5页Journal of Oral Science Research

基　　金：温州市2014年公益性科技计划项目(编号:Y20140559)

摘　　要：目的:系统评价MTA和Ca(OH)_2用于年轻恒牙活髓切断术的临床疗效。方法:计算机检索The Cochrane Library、PubMed、EMbase、CBM、CNKI、VIP和WanFang数据库,查找国内外发表的关于比较MTA与Ca(OH)_2用于年轻恒牙活髓切断术临床随机对照试验(RCT),检索时限均为从建库至2015年3月20日。由2位研究者根据纳入与排除标准独立筛选文献、提取资料和评价纳入研究的方法学质量后,采用RevMan 5.0软件进行Meta分析。结果:最终纳入13个研究,包括926例患牙,其中MTA组458例,Ca(OH)_2组468例。Meta分析结果显示,两组1年[OR=4.43,95%CI(2.38,8.38)]、2年[OR=2.67,95%CI(1.65,4.32)]成功率差异有统计学意义,MTA组1年、2年成功率高于Ca(OH)_2组。结论:现有证据显示,MTA活髓切断术的1年和2年成功率高于Ca(OH)_2,在临床应用中有一定优势。Objective：To systematically review the efficacy of MTA versus Ca（OH）2applied in pulpotomy for immature permanent teeth.Methods：The Cochrane Library,PubMed,EMbase,CBM,CNKI,VIP and WanFang Database,were searched up to March 20,2015 to study the efficacy of MTA versus Ca（OH）2applied for immature permanent teeth pulpotomy.Two reviewers independently screened literature according to the inclusion and exclusion criteria,extracted data and assessed the methodological quality of included studies.Then,Meta-analysis was performed by using RevMan 5.0software.Results：A total of 13 studies involving 926 teeth were included.There were 458 teeth in the MTA group and 468 teeth in the Ca（OH）2group.The results of Meta-analysis showed that compared with the Ca（OH）2group,the MTA group was superior in the first year success rate[OR=4.43,95%CI（2.38,8.38）]and the second year success rate[OR=2.67,95%CI（1.65,4.32）].Conclusion：Based on the current evidences,MTA is superior to Ca（OH）2in pulpotomy for immature permanent teeth.

关 键 词：MTA CA(OH)2 年轻恒牙 活髓切断 系统评价 Meta分析 

分 类 号：R781.05[医药卫生—口腔医学]