慢性透析患者的焦虑和抑郁症状的发生情况及其影响因素分析  

Influence factors of anxiety and depression in uremic patients undergoing hemodialysis and peritoneal dialysis

作　　者：袁杉[1] 王鹏[1] 梁衍[2] 董春萍[2] 张颖[1] 

机构地区：[1]西安市中心医院肾泌科,西安710003 [2]西安市中心医院重症医学科

出　　处：《国际精神病学杂志》2015年第6期70-74,共5页Journal Of International Psychiatry

摘　　要：目的探讨慢性透析患者的焦虑和抑郁症状的发生情况及其影响因素。方法回顾性分析2010年1月-2013年4月期于与我院接受透析的CRF患者134例,采用问卷调查统计患者的背景资料,采用焦虑（SAS）和抑郁（SDS）自评量表进行评分。结果 SDS评分在年龄（〉50岁）与透析时间（〉6个月）上评分较高,差异具有统计学意义（t=7.231、5.957,P〈0.01）,SAS评分在年龄（〉50岁）上评分较高,差异具有统计学意义（t=3.803,P〈0.01）;在年龄（〉50岁）及透析时间（〉6个月）方面抑郁症状出现的比例较高,差异具有统计学意义（χ^2=18.310、22.012,P〈0.01）;而在性别（男性）及年龄（〉50岁）方面焦虑评分较高,差异具有统计学意义（χ^2=10.591、10.836,P〈0.05）;年龄（P=0.046,OR=0.289,95%CI：0.086-0.976）及性别（P=0.003,OR=5.053,95%CI：1.753-14.562）为SAS的危险因素,年龄（P=0.001,OR=6.959,95%CI：2.147-22.556）及透析时间（P=0.000,OR=6.753,95%CI：2.437-18.713）为SDS的危险因素。结论性别、年龄及透析时间对CRF患者的焦虑和抑郁均能产生影响,临床上应采取有针对性的措施进行心理干预,提高临床疗效。Objective To explore the influence factors of anxiety and depression in uremic patients undergoing hemodialysis and peritoneal dialysis. Method 134 cases of patients undergoing hemodialysis and peritoneal dialysis in our hospital from January 2010 - April 2013 were chosen and mood status was evaluated using Self-Rating Anxiety Scale（ SAS） and Self-rating depression scale（ SDS）. Result The SDS were significantly higher in the age（〉 50 years old） and dialysis time（〉 6 months）（ t=7. 231,5. 957,P〈0. 01）,and the SAS were significantly higher in the age（ 〉50 years old）（ t = 3. 803,P〈0. 01）; the depression symptoms appeared to be a higher proportion in age（ 50） and duration of dialysis（〉 6 months）,the difference is statistically significant（ χ^2= 18. 310,22. 012,P〈0. 01）,while the anxiety symptoms were higher in gender（ male） and age（ 〉50 years old）（ χ^2= 10. 591,10. 836,P〈0. 05）; the age（ P = 0. 046,OR = 0. 289,95% CI： 0. 086 - 0. 976） and sex（ P = 0. 003,OR = 5. 053,95% CI：1. 753 - 14. 562） were the risk factors of SAS,and the age（ OR = 6. 959,95%CI： 2. 147 - 22. 556,P = 0. 001） and dialysis time（ P = 0. 000,OR = 6. 753,95%CI： 2. 437 - 18. 713） were the risk factors of SDS. Conclusion The factor of gender,age and duration of dialysis have an effect on anxiety and depression in patients with CRF,and it should be taken to carry out psychological intervention to improve the clinical effect.

关 键 词：慢性肾衰竭 焦虑 抑郁 影响因素 

分 类 号：R749.4[医药卫生—神经病学与精神病学]