彩色多普勒超声联合血清同型半胱氨酸诊断脑血管疾病的价值  

Value of color Doppler ultrasound combined with serum homocysteine in the diagnosis of cerebrovascular disease

作　　者：吴伟晴[1] 廖淑萍[1] 林小兰[1] 黄琼芳[1] 

机构地区：[1]深圳市人民医院暨南大学第二临床医学院体检中心,广东深圳518020

出　　处：《海南医学》2015年第24期3643-3645,共3页Hainan Medical Journal

基　　金：广东省深圳市科技创新委员会资助立项(编号:JSYY20120618144800228)

摘　　要：目的研究彩色多普勒超声联合血清同型半胱氨酸(Hcy)在脑血管疾病诊断中的应用价值。方法选取2013年7月至2015年6月于本院进行诊治的86例脑血管疾病患者为观察组,同时期同龄的86例健康人员为对照组,将两组的彩色多普勒超声检测结果及血清Hcy水平进行比较,并比较观察组中不同出血量出血性疾病及不同梗死面积缺血性脑血管病患者的检测结果。结果观察组的大脑前动脉、中动脉、后动脉、椎动脉及基底动脉的平均血流速度(Vm)和搏动指数(PI)值分别为(60.13±6.17)cm/s和(0.94±0.09)、(69.59±7.10)cm/s和(0.93±0.06)、(46.46±5.25)cm/s和(0.78±0.05)、(35.65±4.63)cm/s和(0.87±0.10)、(35.48±3.96)cm/s和(1.04±0.12),其均差于对照组(P<0.05),血清Hcy水平为(21.24±3.28)μmol/L,高于对照组(P<0.05),且观察组中出血量较多的出血性疾病及梗死面积较大的缺血性脑血管病患者的Vm值低于出血量较少及梗死面积较小的患者,PI值则高于出血量较少及梗死面积较小的患者,差异均有统计学意义(P<0.05)。结论彩色多普勒超声联合血清Hcy在脑血管疾病诊断中的价值较高,对于疾病的诊断及治疗措施的制定均有积极的临床指导作用。Objective To study and analyze the value of color Doppler ultrasound combined with serum homocysteine in the diagnosis of cerebrovascular disease. Methods Eighty-six patients with cerebrovascular disease in our hospital from July 2013 to June 2015 were selected as the observation group, and 86 healthy persons with the same age at the same time were selected as the control group. Then the detection results of color Doppler ultrasound and serum homocysteine of two groups were compared. The detection results of observation group with different bleeding volume of hemorrhagic disease and different infarct size of ischemic disease were compared. Results The mean blood flow velocity（Vm） and pulsatility index（PI） of cerebral anterior artery, middle artery, posterior artery,vertebral artery, basilar artery of the observation group were（60.13±6.17） cm/s and（0.94±0.09）,（69.59±7.10） cm/s and（0.93 ± 0.06）,（46.46 ± 5.25） cm/s and（0.78 ± 0.05）,（35.65 ± 4.63） cm/s and（0.87 ± 0.10）,（35.48 ± 3.96） cm/s and（1.04±0.12）, respectively, which were all worse than those in the control group（P〈0.05）. The serum homocysteine of the observation group was（21.24 ± 3.28） μ mol/L, which was significantly higher than that of the control group（P〈0.05）. In the observation group, the Vm of patients with more bleeding volume of hemorrhagic disease and larger infarct size of ischemic disease were significantly lower than those of patients with less bleeding volume of hemorrhagic disease and smaller infarct size of ischemic disease, but PI was significantly higher（P〈0.05）. Conclusion The value of color Doppler ultrasound combined with serum homocysteine in the diagnosis of cerebrovascular disease are relatively high, and it has active role for the diagnosis of disease and constitution of treatment measures.

关 键 词：彩色多普勒超声 血清同型半胱氨酸 脑血管疾病 诊断 

分 类 号：R743[医药卫生—神经病学与精神病学]