不同年龄段妇科门诊患者TCT筛查结果分析  

Clinical analysis of outpatients' cervix screening by TCT in different age groups

作　　者：叶常鸿 王燕[1] 张敦兰[1] 周利敏[1] 陈璐[1] 胡俊波[1] 

机构地区：[1]湖北省妇幼保健院妇科,武汉430070

出　　处：《现代泌尿生殖肿瘤杂志》2015年第5期295-298,共4页Journal of Contemporary Urologic and Reproductive Oncology

摘　　要：目的：通过对湖北省妇幼保健院妇科门诊就诊的不同年龄段患者的宫颈液基细胞学检测（TCT）筛查结果进行回顾性分析,了解不同年龄段宫颈病变的分布状况.方法收集我院2013年1月至2013年12月门诊就诊患者的 TCT 检查结果,将检查结果按照不同年龄分组,分析各年龄组的检出结果,并进行统计学分析.结果19024例 TCT 检测结果中,检测到诊断意义不明的不典型鳞状细胞（ASCUS）及以上的宫颈病变共1303例,检出率为6.85％,其中 ASCUS 676例（3.55％）,检出率最高.宫颈病变类型中,ASCUS 所占比例最大（51.88％,676例）.36~45岁组和46~55岁组宫颈病变的阳性检出率最高,分别为10.98％（606例）、9.01％（377例）,两组间检出率与其他组间比较差异具有统计学意义（P ＜0.05）.在36~45岁组 ASCUS 检出率最高（7.47％,412例）；46~55岁组上皮内低度病变（LSIL）检出率最高（4.49％,188例）；＞55岁年龄组（56~65岁和＞66岁组）上皮内高度病变（HSIL）及以上病变检出率最高（2.05％,71例）（P ＜0.05）.55岁以上,宫颈 TCT 检出的病变级别与年龄呈正相关（r s ＝0.51,P ＜0.05）.结论宫颈病变程度随年龄增加而加重；加强36~55岁年龄段的宫颈病变筛查检测,有利于早发现及早治疗.Objective To evaluate the incidence rate of cervical lesions in different age groups. Methods A retrospective review was performed on the data of cervix cytology from 1 9 024 outpa-tients in the maternal and child care service centre of Hubei province,from January 2013 to Decem-ber 2013. Those outpatients were divided into different age groups. We described the incidence rates of cervical lesions which detected by cytology in each age groups. Results We defined the positive specimens as ASCUS （atypical squamous cell of undermined significance）or worse,which including LSIL （low-grade squamous intraepithelial lesion）,HSIL （high-grade squamous intraepithelial le-sion）,cervical cancer. Of 1 9 024 cases by cytology,1 303 cases were detected positive specimens, the positive detecting rate was 6.85%. As one of the positive cases,ASCUS is the highest incidence rate （3.55%,676 cases ）. ASCUS makes up the largest percentage of the positive specimens （5 1.88%,676 cases）. The groups of 36-45 years and 46-55 years old were proved to be ranked first （10.98%,606 cases）and second （9.01%,377 cases）.There was statistically significant different between those two groups and others. Incidence rate of ASCUS was proved highest in the group of 36-45 years old （7.47%,412 cases）. Incidence rate of LSIL was proved highest in the group of 46-55 years old （4.49%,188 cases）. Incidence rate of HSIL or the worse was proved highest in the group of 〉55 years old （2.05%,71 cases）. Above 55 years old,the level of cervical lesion and ages were positively correlated （r s =0.5 1,P 〈0.05）. Conclusions The cervical lesion levels grow with age. In order to detect and treat cervical lesion as early,we should strengthen the cervical screening especially in 36-55 years old.

关 键 词：宫颈病变 TCT 筛查 年龄组 

分 类 号：R737.33[医药卫生—肿瘤]