上海宝山地区胃食管反流病流行学研究及生活质量评价  

Epidemiologic investigation of gastroesophageal reflux disease in the population of Shanghai Baoshan district

作　　者：李爽[1,2] 周康年[1] 侯立新[1] 黄兰蔚[1] 崔永康[1] 梅灿勇 许多[1] 刘成海[2] 

机构地区：[1]上海中医药大学附属曙光医院宝山分院消化内科,上海200000 [2]上海中医药大学附属曙光医院肝病研究所,上海200000

出　　处：《临床消化病杂志》2015年第6期333-336,共4页Chinese Journal of Clinical Gastroenterology

摘　　要：[目的]探讨上海宝山地区人群胃食管反流病（GERD）的患病率及发病危险因素。[方法]采用中文版反流性疾病问卷（RDQ），应用随机、整群、分层抽样方法对上海宝山地区≥18岁居民进行调查，调查方式为面试。[结果]实际调查3126例（男1635例，女1491例），年龄18～87（43．5±17．1）岁；按RDQ评分≥12分定义，GERD的患病率为8．5％（266／3126）；30～〈40岁人群GERD患病率与其他年龄比较，差异有统计学意义（P〈0．05）；男性患病率高于女性，但两性比较差异无统计学意义（P〉o．05）。GERD组伴发口咽疾病、鼾症、哮喘的比例明显高于非GERD组，2组比较差异有统计学意义（P〈0．05）；饱食、便秘、吸烟是GERD患病的独立危险因素。GERD组SF-36量表8个维度生活质量评分和量表总评分均明显低于非GERD组，差异有统计学意义（P〈0．05）。[结论]上海宝山地区GERD患病率略高于上海市水平，GERD患者生活质量较正常健康人群明显下降。[Objective] To assess the population-based prevalence of gatroesophageal reflux disease （GERD）and risk factors in Baoshan district. [Methods]From September 2013 to December 2013,a face-to- face interview was carried out in a randomly sampled population of Baoshan district by using a validated Chinese version of Reflux Disease Questionnaire（RDQ）to assess the prevalence of GERD. [Results]A total of 3126 residents（1635 males and 1491 females）were investigated actually. The responders ranged in age from 18 to 87 years,with a mean age of 43.5±17.1 years. The prevalence of GERD in the population of Baoshan district was 8.5% according to the definition（RDQ score≥12）. The prevalence of GERD in age from 30 to 40 years was higher than that in other years though no significant difference was found（P〉0.05）. The prevalence of GERD in male was slightly higher than that in female,but no significant difference（P〉0.05）. GERD group associated with the oropharyngeal disease,apnea and asthma was significantly higher than non-GERD Group, the difference was statistically significant （P 〈 0.05）. Satiety, constipation,smoking are independent risk factors for GERD. The quality of life score（SF-36）was significantly lower in GERD patients than in healthy controls. [Conclusion]The prevalence of GERD in Baoshan district was slighter higher than that reported in Shanghai. The quality of life declines obviously in GERD patients when compared with healthy controls.

关 键 词：胃食管反流病 流行病学 宝山地区 SF-36 健康调查简表 

分 类 号：R571[医药卫生—消化系统]