原发性三叉神经痛三叉神经根部病因观察  

Etiologic investigation of the root of trigeminal nerve for primary trigeminal neuralgia

作　　者：赵永宏[1] 蔡其刚[1] 翁维[1] 

机构地区：[1]解放军第477医院耳鼻咽喉头颈外科,湖北襄阳441003

出　　处：《中国耳鼻咽喉颅底外科杂志》2015年第6期486-488,共3页Chinese Journal of Otorhinolaryngology-skull Base Surgery

摘　　要：目的分析原发性三叉神经痛(trigeminal neuralgia,TN)的病因和发病机制。方法选择三叉神经痛患者120例,在显微血管减压术中观察三叉神经根部病变情况。结果三叉神经根部可见血管压迫105例(105/120,87.5%)、蛛网膜粘连115例(115/120,95.8%)、神经根萎缩12例(12/120,10%)、血管脂质斑20例(20/120,16.7%)。结论三叉神经痛的主要病因是责任血管压迫、神经根萎缩退变,蛛网膜粘连、动脉硬化是其主要诱因。微血管减压术(microvascular decompression,MVD)或神经根部分切断术临床可缓解患者原发三叉神经痛。Objective To explore the etiology and pathogenesis of primary trigeminal neuralgia （TN）. Methods 120 patients suffering from TN were chosen for observing the pathological changes of the root of trigeminal nerve during microvascular decompression. Results The pathological changes of the root of trigeminal nerve included neurovascular compression in 105 cases （87.5%）, arachnoids adhesion in 115（95.8% ）, atrophy of the nerve root in 12（ 10% ） and arteriosclerosis plague in 20 （ 16.7% ）. Conclusions The main etiological factors in TN are compression of offending vessels and atrophy of nerve root, and the triggering factors are arachnoids adhesion and arteriosclerosis. Microvascular decompression and selective trigeminal nerve rhizotomy can effectively relieve the symptoms of TN.

关 键 词：三叉神经痛 病因学 病理状态 微血管减压术 

分 类 号：R745.11[医药卫生—神经病学与精神病学]